1H-Pyrrole-2-carboxylic acid, 3-hydroxy-1-methyl-, 1,1-dimethylethyl ester

Base Information

Chemical Name:1H-Pyrrole-2-carboxylic acid, 3-hydroxy-1-methyl-, 1,1-dimethylethyl ester
CAS No.:65171-94-0
Molecular Formula:C10H15NO3
Molecular Weight:197.23100
Hs Code.:

Synonyms:3-hydroxy-1-methyl-pyrrole-2-carboxylic acid tert-butyl ester;3-Hydroxy-1-methyl-1H-pyrrole-2-carboxylic acid tert-butyl ester;tert.-Butyl-1-methyl-3-hydroxypyrrol-2-carboxylat;

Suppliers and Price of 1H-Pyrrole-2-carboxylic acid, 3-hydroxy-1-methyl-, 1,1-dimethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
3-hydroxy-1-methyl-1H-Pyrrole-2-carboxylicacid1,1-dimethylethylester 97.00%
25G
$ 7910.00

AccelPharmtech
3-hydroxy-1-methyl-1H-Pyrrole-2-carboxylicacid1,1-dimethylethylester 97.00%
5G
$ 4220.00

AccelPharmtech
3-hydroxy-1-methyl-1H-Pyrrole-2-carboxylicacid1,1-dimethylethylester 97.00%
1G
$ 2460.00

Total 1 raw suppliers

Chemical Property of 1H-Pyrrole-2-carboxylic acid, 3-hydroxy-1-methyl-, 1,1-dimethylethyl ester

Chemical Property:

PSA：51.46000
LogP:1.68600

Purity/Quality:

98% ^*data from raw suppliers

3-hydroxy-1-methyl-1H-Pyrrole-2-carboxylicacid1,1-dimethylethylester 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1H-Pyrrole-2-carboxylic acid, 3-hydroxy-1-methyl-, 1,1-dimethylethyl ester

There total 2 articles about 1H-Pyrrole-2-carboxylic acid, 3-hydroxy-1-methyl-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: t-butyl 2,3-dioxo-pent-4-enoate hydrate

: 74-89-5
methylamine

: 65171-94-0
t-butyl 3-hydroxy-1-methylpyrrole-2-carboxylate

Guidance literature:: With silica gel; Yield given. Multistep reaction; 1.) dichloromethane, rt, 30 min; 2.) overnight;
DOI:10.1016/S0040-4039(00)99565-0

Reference yield:

: 65171-94-0
t-butyl 3-hydroxy-1-methylpyrrole-2-carboxylate

Guidance literature:: tert.-Butyl-4-carboxy-pyrrol-2-carboxylat (10d), β-Picolin;

Reference yield:

: 65171-94-0
t-butyl 3-hydroxy-1-methylpyrrole-2-carboxylate

: 312299-01-7
3-benzoyloxy-1-methylpyrrole-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / pyridine / CH₂Cl₂ / 1 h / 0 - 20 °C

2: DIEA; TMSOTf / dioxane / 4 h / 20 °C

With pyridine; trimethylsilyl trifluoromethanesulfonate; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; dichloromethane;
DOI:10.1021/ja001692u