Papaverinol

Base Information

Chemical Name:Papaverinol
CAS No.:482-76-8
Molecular Formula:C20H21 N O5
Molecular Weight:355.39
Hs Code.:
European Community (EC) Number:207-585-3
NSC Number:121864
DSSTox Substance ID:DTXSID70964029
Nikkaji Number:J182.224A
ChEMBL ID:CHEMBL207931
Mol file:482-76-8.mol

Synonyms:papaverinol

Suppliers and Price of Papaverinol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(6,7-DIMETHOXY-ISOQUINOLIN-1-YL)-(3,4-DIMETHOXY-PHENYL)-METHANOL 95.00%
5MG
$ 496.84

Total 8 raw suppliers

Chemical Property of Papaverinol

Chemical Property:

Melting Point:138-139 °C
Boiling Point:534.6°Cat760mmHg
PKA:12.15±0.20(Predicted)
Flash Point:277.1°C
PSA：70.04000
Density:1.223g/cm³
LogP:3.35090
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:355.14197277
Heavy Atom Count:26
Complexity:436

Purity/Quality:

99% ^*data from raw suppliers

(6,7-DIMETHOXY-ISOQUINOLIN-1-YL)-(3,4-DIMETHOXY-PHENYL)-METHANOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C(C2=NC=CC3=CC(=C(C=C32)OC)OC)O)OC

Technology Process of Papaverinol

There total 24 articles about Papaverinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.6%

: 58-74-2
Papaverine

: 482-76-8
papaverinol

: 13-(3,4-dimethoxy-phenyl)-2,3,8,9-tetramethoxy-6a-aza-12a-azonia-dibenzo[a,g]fluorene

Guidance literature:: With mercury(II) diacetate; In acetic acid; at 20 - 70 ℃; for 26h;
DOI:10.1002/1521-4184(200204)335:4<167::AID-ARDP167>3.0.CO;2-O

Reference yield: 81.0%

: 522-57-6
papaveraldine

: 482-76-8
papaverinol

Guidance literature:: With sodium tetrahydroborate; In methanol; dichloromethane; for 12h;
DOI:10.1111/j.2042-7158.1992.tb03617.x

Reference yield: 42.0%

: 15248-39-2
6,7-dimethoxyisoquinoline

: 120-14-9
3,4-dimethoxy-benzaldehyde

: 482-76-8
papaverinol

Guidance literature:: 6,7-dimethoxyisoquinoline; With 2,2,6,6-tetramethylpiperidinylmagnesium chloride lithium chloride complex; In tetrahydrofuran; at 25 ℃; for 4h; Inert atmosphere; Schlenk technique;

3,4-dimethoxy-benzaldehyde; In tetrahydrofuran; at 0 - 25 ℃; for 16h; regioselective reaction; Inert atmosphere; Schlenk technique;
DOI:10.1039/c5ob00926j