Methyl 5-hydroxy-4,5-dimethyl-2-oxo-2,5-dihydrofuran-3-carboxylate

Base Information

Chemical Name:Methyl 5-hydroxy-4,5-dimethyl-2-oxo-2,5-dihydrofuran-3-carboxylate
CAS No.:60971-98-4
Molecular Formula:C8H10O5
Molecular Weight:186.162
Hs Code.:
UNII:18I71AG560
DSSTox Substance ID:DTXSID00976453
Wikidata:Q27252005

Synonyms:60971-98-4;5-Hydroxy-3-(methoxycarbonyl)-4,5-dimethyl-3,4-didehydro-gamma-butyrolactone;Methyl 5-hydroxy-4,5-dimethyl-2-oxo-2,5-dihydrofuran-3-carboxylate;18I71AG560;CCRIS 4978;2,5-Dihydro-5-hydroxy-4,5-dimethyl-2-oxo-3-furancarboylic acid, methyl ester;UNII-18I71AG560;DTXSID00976453;Q27252005;3-FURANCARBOXYLIC ACID, 2,5-DIHYDRO-5-HYDROXY-4,5-DIMETHYL-2-OXO-, METHYL ESTER

Suppliers and Price of Methyl 5-hydroxy-4,5-dimethyl-2-oxo-2,5-dihydrofuran-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5-HYDROXY-3-(METHOXYCARBONYL)-4,5-DIMETHYL-3,4-DIDEHYDRO-GAMMA-BUTYROLACTONE 95.00%
5MG
$ 501.45

Total 0 raw suppliers

Chemical Property of Methyl 5-hydroxy-4,5-dimethyl-2-oxo-2,5-dihydrofuran-3-carboxylate

Chemical Property:

Vapor Pressure:5.81E-07mmHg at 25°C
Boiling Point:369.5°Cat760mmHg
Flash Point:153.5°C
PSA：72.83000
Density:1.343g/cm³
LogP:-0.25880
XLogP3:-0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:186.05282342
Heavy Atom Count:13
Complexity:304

Purity/Quality:: 5-HYDROXY-3-(METHOXYCARBONYL)-4,5-DIMETHYL-3,4-DIDEHYDRO-GAMMA-BUTYROLACTONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C(=O)OC1(C)O)C(=O)OC

Technology Process of Methyl 5-hydroxy-4,5-dimethyl-2-oxo-2,5-dihydrofuran-3-carboxylate

There total 1 articles about Methyl 5-hydroxy-4,5-dimethyl-2-oxo-2,5-dihydrofuran-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 60971-97-3
2,5-dihydro-5-hydroxy-4,5-dimethyl-2-oxo-3-furancarboxylic acid

: 60971-98-4
2,5-dihydro-5-hydroxy-4,5-dimethyl-2-oxo-3-furancarboxylic acid methyl ester

Guidance literature:: In diethyl ether;
DOI:10.1021/ja00527a046

Reference yield: 76.0%

: 60971-98-4
2,5-dihydro-5-hydroxy-4,5-dimethyl-2-oxo-3-furancarboxylic acid methyl ester

: 6277-50-5
methyl 3-methylene-4-oxopentanoate

Guidance literature:: at 140 ℃;
DOI:10.1021/ja00527a046

Reference yield:

: 60971-98-4
2,5-dihydro-5-hydroxy-4,5-dimethyl-2-oxo-3-furancarboxylic acid methyl ester

: 60972-00-1
2,5-dihydro-4-methyl-5-<(1-methyl-2-oxocyclohexyl)methyl>-2-oxo-3-furancarboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / phosphorus pentoxide, methanesulphonic acid / 1.5 h / Ambient temperature

2: 50 percent / titanium tetrachloride / CH₂Cl₂ / 0.07 h / -78 °C

With phosphorus pentaoxide; methanesulfonic acid; titanium tetrachloride; In dichloromethane;
DOI:10.1021/ja00527a046