6277-50-5

Basic information

• Product Name: methyl 3-methylidene-4-oxopentanoate
• CAS NO: 6277-50-5
• Molecular Formula: C₇H₁₀O₃
• Molecular Weight: 142.1525
• Mol File: 6277-50-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 223.5°C at 760 mmHg
• Flash Point: 91.4°C
• Density: 1.018g/cm³
• Vapor Pressure: 0.0959mmHg at 25°C
• Refractive Index: 1.427
• CAS DataBase Reference: methyl 3-methylidene-4-oxopentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-methylidene-4-oxopentanoate(6277-50-5)
• EPA Substance Registry System: methyl 3-methylidene-4-oxopentanoate(6277-50-5)

Safety Data

• Hazardous Substances Data: 6277-50-5(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 39265-95-7 methyl 3-acetyl-4-oxopentanoate 
• 60971-98-4 2,5-dihydro-5-hydroxy-4,5-dimethyl-2-oxo-3-furancarboxylic acid methyl ester 
• 624-45-3 levulinic acid methyl ester 
• 50-99-7 D-glucose 
• 98-01-1 furfural 
• 58-86-6 D-xylose 
• 60971-97-3 2,5-dihydro-5-hydroxy-4,5-dimethyl-2-oxo-3-furancarboxylic acid 

Downstream Products

• 74063-85-7 methyl 4-oxo-3-(phenylthiomethyl)pentanoate 

Relevant articles and documents

PROCESS FOR THE DIRECT ALPHA-METHYLENATION OF KETONES

The invention relates to a process for preparing an α-methylene ketone comprising the step of reacting a ketone with formaldehyde in the presence of a catalyst which is an organic compound comprising at least one acid function or the corresponding salt, ester or amide thereof and at least one amine function or the corresponding ammonium salt, or a zwitterion thereof.

A convenient synthesis of α-functional alkyl vinyl ketones

Reaction of 2-functional alkyl-1,3-ketones with 30% aqueous formaldehyde using aqueous 6-10M potassium carbonate solution as base, afforded α-functional alkyl vinyl ketones in good yields.