N-(1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)acetamide

Base Information

Chemical Name:N-(1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)acetamide
CAS No.:10506-95-3
Molecular Formula:C₁₀H₈N₂O₃
Molecular Weight:204.185
Hs Code.:
NSC Number:229337
DSSTox Substance ID:DTXSID30310609
Wikidata:Q82059656
Mol file:10506-95-3.mol

Synonyms:10506-95-3;4-acetylaminophthalimid;N-(1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)acetamide;NSC 229337;F1105-0116;Acetamide, N-(2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl)-;NSC229337;Oprea1_125255;SCHEMBL5838218;DTXSID30310609;STL120318;AKOS005232564;NSC-229337;N-(1,3-dioxoisoindolin-5-yl)acetamide

Suppliers and Price of N-(1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of N-(1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)acetamide

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.451g/cm³
XLogP3:-0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:204.05349212
Heavy Atom Count:15
Complexity:327

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=CC2=C(C=C1)C(=O)NC2=O

Technology Process of N-(1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)acetamide

There total 4 articles about N-(1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 3676-85-5
4-aminophthalimide

: 75-36-5
acetyl chloride

: 10506-95-3
N-(1,3-dioxoisoindolin-5-yl)acetamide

Guidance literature:: With pyridine; at 0 ℃; for 2h; Inert atmosphere;
DOI:10.1021/jacs.9b00394

Reference yield:

: 136918-14-4,85-41-6
phthalimide

: 10506-95-3
N-(1,3-dioxoisoindolin-5-yl)acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: HNO₃+H₂SO₄ / Darstellung; Nitrierung

2: SnCl₂; aqueous HCl

With hydrogenchloride; sulfuric acid; nitric acid; tin(ll) chloride;
DOI:10.1039/jr9310000079

Reference yield:

: 89-40-7
4-nitrophthalimide

: 10506-95-3
N-(1,3-dioxoisoindolin-5-yl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: SnCl₂; aqueous HCl

With hydrogenchloride; tin(ll) chloride;
DOI:10.1039/jr9310000079