Methyl 1-oxo-2-phenyl-1lambda~5~-quinoline-4-carboxylate

Base Information

Chemical Name:Methyl 1-oxo-2-phenyl-1lambda~5~-quinoline-4-carboxylate
CAS No.:65417-19-8
Molecular Formula:C17H13NO3
Molecular Weight:279.295
Hs Code.:
DSSTox Substance ID:DTXSID70512862
Wikidata:Q82372287

Synonyms:65417-19-8;DTXSID70512862;Methyl 1-oxo-2-phenyl-1lambda~5~-quinoline-4-carboxylate

Suppliers and Price of Methyl 1-oxo-2-phenyl-1lambda~5~-quinoline-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Methyl 1-oxo-2-phenyl-1lambda~5~-quinoline-4-carboxylate

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:279.08954328
Heavy Atom Count:21
Complexity:367

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=CC(=[N+](C2=CC=CC=C21)[O-])C3=CC=CC=C3

Technology Process of Methyl 1-oxo-2-phenyl-1lambda~5~-quinoline-4-carboxylate

There total 5 articles about Methyl 1-oxo-2-phenyl-1lambda~5~-quinoline-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 64880-78-0
methyl quinoline-4-carboxylate 1-oxide

: 62-53-3
aniline

: 65417-19-8
methyl 2-phenylquinoline-4-carboxylate 1-oxide

Guidance literature:: With tert.-butylnitrite; In acetonitrile; at 40 ℃; for 17h; Reagent/catalyst; regioselective reaction; Inert atmosphere; Green chemistry;
DOI:10.1021/acs.oprd.6b00117

Reference yield:

: 4546-48-9
methyl 2-phenylquinoline-4-carboxylate

: 65417-19-8
methyl 2-phenylquinoline-4-carboxylate 1-oxide

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 - 20 ℃; for 24h;
DOI:10.1002/chem.201806373

Reference yield:

: 132-60-5
cinchophen

: 65417-19-8
methyl 2-phenylquinoline-4-carboxylate 1-oxide

Guidance literature:: Multi-step reaction with 2 steps

1: 35percent H₂O₂ / acetic acid / 7 h / 90 - 95 °C

2: conc. H₂SO₄ / 12 h / Heating

With sulfuric acid; dihydrogen peroxide; In acetic acid;
DOI:10.1248/cpb.28.1157