5-BROMO-2-(2-NAPHTHYLOXY)ANILINE

Base Information

• Chemical Name: 5-BROMO-2-(2-NAPHTHYLOXY)ANILINE
• CAS No.: 65457-11-6
• Molecular Formula: C16H12BrNO
• Molecular Weight: 314.181
• Mol file: 65457-11-6.mol

Synonyms:

Chemical Property of 5-BROMO-2-(2-NAPHTHYLOXY)ANILINE

Chemical Property:

• PSA: 35.25000
• LogP: 5.55800

Purity/Quality:

98%min ^*data from raw suppliers

5-Bromo-2-(2-naphthyloxy)aniline ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

Useful:

Technology Process of 5-BROMO-2-(2-NAPHTHYLOXY)ANILINE

There total 1 articles about 5-BROMO-2-(2-NAPHTHYLOXY)ANILINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 5-bromo-2-(naphthalen-2-yloxy)aniline (65457-11-6)

Guidance literature:

4-Brom-2-nitrophenyl-β-naphthylether V/A., Δ mit SnCl2*(H2O)2/konz. HCl;

DOI:10.1248/yakushi1947.96.5_663

Reference yield: 80.0%

Dimethyldisulphide (624-92-0) + 5-bromo-2-(naphthalen-2-yloxy)aniline (65457-11-6) → (5-bromo-2-(naphthalen-2-yloxy)phenyl)(methyl)sulfane

Guidance literature:

With tert.-butylnitrite; at 90 ℃; for 0.5h; Inert atmosphere;

DOI:10.1002/cmdc.201800158

Reference yield:

5-bromo-2-(naphthalen-2-yloxy)aniline (65457-11-6) → 2-(4-bromo-2-(methylsulfonyl)phenoxy)naphthalene

Guidance literature:

Multi-step reaction with 2 steps

1: tert.-butylnitrite / 0.5 h / 90 °C / Inert atmosphere

2: oxone||potassium monopersulfate triple salt / water; acetone / 17 h / 0 - 20 °C

With tert.-butylnitrite; oxone||potassium monopersulfate triple salt; In water; acetone;

DOI:10.1002/cmdc.201800158

Refernces