9-ACETAMIDOACRIDINE

Base Information

• Chemical Name: 9-ACETAMIDOACRIDINE
• CAS No.: 23043-52-9
• Molecular Formula: C15H12 N2 O
• Molecular Weight: 236.273
• Hs Code.: 2933990090
• NSC Number: 64014
• UNII: KDZ3G5O0NV
• DSSTox Substance ID: DTXSID60177601
• Nikkaji Number: J54.047A
• Wikidata: Q83047916
• Mol file: 23043-52-9.mol

Synonyms:Acridine,9-acetamido- (6CI,7CI); 9-Acetamidoacridine; 9-Acetylaminoacridine;N-9-Acridinylacetamide; NSC 64014

Chemical Property of 9-ACETAMIDOACRIDINE

Chemical Property:

• Vapor Pressure: 6.99E-11mmHg at 25°C
• Boiling Point: 519.2°Cat760mmHg
• Flash Point: 267.8°C
• PSA: 41.99000
• Density: 1.284g/cm³
• LogP: 3.41940
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 236.094963011
• Heavy Atom Count: 18
• Complexity: 296

Purity/Quality:

99% ^*data from raw suppliers

9-ACETAMIDOACRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC1=C2C=CC=CC2=NC3=CC=CC=C31

Technology Process of 9-ACETAMIDOACRIDINE

There total 3 articles about 9-ACETAMIDOACRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

acetamide (60-35-5) + acridine (260-94-6) → N-(acridin-9-yl)acetamide (23043-52-9)

Guidance literature:

acetamide; With sodium hydride; In dimethyl sulfoxide; paraffin oil; for 0.5h;

acridine; With potassium hexacyanoferrate(III); In dimethyl sulfoxide; paraffin oil; at 20 ℃; for 10h;

DOI:10.1007/s10593-016-1841-7

Reference yield: 67.8%

acetic anhydride (108-24-7) + acridin-9-amine hydrochloride (134-50-9) → N-(acridin-9-yl)acetamide (23043-52-9)

Guidance literature:

In pyridine; at 70 ℃; for 24h;

DOI:10.1271/bbb.58.1420

Reference yield: 66.0%

aminacrine (110166-26-2,90-45-9) + acetic anhydride (108-24-7) → N-(acridin-9-yl)acetamide (23043-52-9)

Guidance literature:

In N,N-dimethyl-formamide; at 60 ℃; for 1h;

DOI:10.1021/jo00250a017

upstream raw materials:

aminacrine

acetic anhydride

acridin-9-amine hydrochloride

acetamide

Downstream raw materials:

10H-acridin-9-one