3,4-dihydroisonoracronycine

Base Information

• Chemical Name: 3,4-dihydroisonoracronycine
• CAS No.: 50868-43-4
• Molecular Formula: C₁₉H₁₉NO₃
• Molecular Weight: 309.365
• Hs Code.: 2934999090
• Mol file: 50868-43-4.mol

Synonyms:Dihydroisonoracronycine;Dihydronorisoacronycine; Nordihydroisoacronycine; O-Demethyldihydroisoacronycine

Chemical Property of 3,4-dihydroisonoracronycine

Chemical Property:

• Vapor Pressure: 1.66E-11mmHg at 25°C
• Boiling Point: 521.8°Cat760mmHg
• Flash Point: 269.4°C
• PSA: 51.46000
• Density: 1.245g/cm³
• LogP: 3.50090

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,4-dihydroisonoracronycine

There total 6 articles about 3,4-dihydroisonoracronycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-methoxy-3,3,12-trimethyl-3,12-dihydro-pyrano[2,3-c]acridin-7-one; hydrochloride (70509-95-4) → 5-hydroxy-2,2,11-trimethyl-2,3,4,11-tetrahydro-pyrano[3,2-b]acridin-6-one (50868-43-4) + N-methyl-1,3-dihydroxyacridone (28333-02-0) + noracronycine (13161-79-0) + 14-Hydroxy-2,5,5,8-tetramethyl-5,8-dihydro-6-oxa-8-aza-benzo[a]naphthacen-13-one

Guidance literature:

In neat (no solvent); at 250 ℃; for 2.5h; Yield given. Further byproducts given. Yields of byproduct given;

DOI:10.3987/COM-96-7442

Reference yield:

6-methoxy-3,3,12-trimethyl-3,12-dihydro-pyrano[2,3-c]acridin-7-one; hydrochloride (70509-95-4) → 5-hydroxy-2,2,11-trimethyl-2,3,4,11-tetrahydro-pyrano[3,2-b]acridin-6-one (50868-43-4) + N-methyl-1,3-dihydroxyacridone (28333-02-0) + noracronycine (13161-79-0) + 1,2-dihydronoracronycine (17014-70-9) + 1,3-Dihydroxy-2,10-dimethyl-10H-acridin-9-one + 4-Hydroxy-2,2,10-trimethyl-3,10-dihydro-2H-1-oxa-10-aza-cyclopenta[b]anthracen-5-one

Guidance literature:

In neat (no solvent); at 250 ℃; for 2.5h; Product distribution;

DOI:10.3987/COM-96-7442

Reference yield:

1,3-dihydroxy-10-methyl-4-(3-methylbut-2-enyl)-9(10H)-acridinone (glyocitrine-II) (28333-13-3) → 5-hydroxy-2,2,11-trimethyl-2,3,4,11-tetrahydro-pyrano[3,2-b]acridin-6-one (50868-43-4) + 1,2-dihydronoracronycine (17014-70-9) + 3,3,7,7,14-Pentamethyl-2,3,5,6,7,14-hexahydro-1H-4,8-dioxa-14-aza-benzo[b]triphenylen-9-one (88206-45-5)

Guidance literature:

With formic acid; 1.) 90 deg C - 100 deg C, 4 h, 2.) room temperature, overnight;

upstream raw materials:

5-hydroxy-2,2-dimethyl-2,3,4,11-tetrahydro-pyrano[3,2-b]acridin-6-one

methyl iodide

1,3-dihydroxy-10-methyl-4-(3-methylbut-2-enyl)-9(10H)-acridinone (glyocitrine-II)

6-methoxy-3,3,12-trimethyl-3,12-dihydro-pyrano[2,3-c]acridin-7-one; hydrochloride