1-[4-(3-BROMOPROPOXY)PHENYL]ETHANONE

Base Information

• Chemical Name: 1-[4-(3-BROMOPROPOXY)PHENYL]ETHANONE
• CAS No.: 65623-98-5
• Molecular Formula: C11H13BrO2
• Molecular Weight: 257.127
• Mol file: 65623-98-5.mol

Synonyms:

Chemical Property of 1-[4-(3-BROMOPROPOXY)PHENYL]ETHANONE

Chemical Property:

• PSA: 26.30000
• LogP: 3.05300

Purity/Quality:

99% ^*data from raw suppliers

1-[4-(3-Bromopropoxy)-phenyl]-ethanone 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-[4-(3-BROMOPROPOXY)PHENYL]ETHANONE

There total 2 articles about 1-[4-(3-BROMOPROPOXY)PHENYL]ETHANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.6%

1,3-dibromo-propane (109-64-8) + 4-Hydroxyacetophenone (99-93-4) → 1-[4-(3-bromopropoxy)phenyl]ethanone (65623-98-5)

Guidance literature:

With N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate; In ethyl acetate; Reflux;

DOI:10.1111/cbdd.13371

Reference yield: 82.0%

→ 1-[4-(3-bromopropoxy)phenyl]ethanone (65623-98-5)

Guidance literature:

With potassium carbonate; potassium iodide; In acetonitrile; for 3h; Reflux;

Reference yield: 99.0%

1-[4-(3-bromopropoxy)phenyl]ethanone (65623-98-5) + silver(I) trifluoromethanethiolate (811-68-7) → 1-(4-(3-((trifluoromethyl)thio)propoxy)phenyl)ethanone

Guidance literature:

With tetra-(n-butyl)ammonium iodide; In acetone; at 80 ℃; Schlenk technique; Inert atmosphere;

DOI:10.1002/cjoc.201500905

upstream raw materials:

1,3-dibromo-propane

4-Hydroxyacetophenone

Downstream raw materials:

3-(4-acetylphenoxy)propyl acetate

3-{3-[3-(4-Acetyl-phenoxy)-propoxy]-phenyl}-propionic acid ethyl ester

3-(3-{3-[4-(1H-Pyrazol-3-yl)-phenoxy]-propoxy}-phenyl)-propionic acid ethyl ester

1-[4-(3-hydroxypropoxy)phenyl]ethanone