1,4-Benzenediamine, 2,3,5,6-tetrafluoro-

Base Information

• Chemical Name: 1,4-Benzenediamine, 2,3,5,6-tetrafluoro-
• CAS No.: 1198-64-7
• Deprecated CAS: 69680-23-5
• Molecular Formula: C6H4 F4 N2
• Molecular Weight: 180.105
• Hs Code.: 2921519090
• European Community (EC) Number: 214-837-6
• NSC Number: 114704
• DSSTox Substance ID: DTXSID5061611
• Nikkaji Number: J130.385F
• Wikidata: Q81989561
• Mol file: 1198-64-7.mol

Synonyms:1198-64-7;2,3,5,6-Tetrafluoro-1,4-phenylenediamine;2,3,5,6-Tetrafluorobenzene-1,4-diamine;1,4-Benzenediamine, 2,3,5,6-tetrafluoro-;1,4-Diaminotetrafluorobenzene;1,4-Diamino-2,3,5,6-tetrafluorobenzene;Tetrafluoro-p-phenylenediamine;2,3,5,6-Tetrafluorophenylene-1,4-diamine;EINECS 214-837-6;p-Phenylenediamine, 2,3,5,6-tetrafluoro-;tetrafluorobenzene-1,4-diamine;NSC114704;YSWG732;Tetrafluoro-1,4-benzenediamine;SCHEMBL1378109;DTXSID5061611;MFCD00039767;AKOS006230416;NSC 114704;NSC-114704;p-Phenylenediamine,3,5,6-tetrafluoro-;2,3,5,6-Tetrafluoro-p-phenylenediamine;AS-64499;1,4-Benzenediamine, 2,3,5,6-tetrafluoro;2,3,5,6-Tetrafluoro-1,4-benzenediamine #;AM20020279;CS-0170372;FT-0633468;T1110;T71628;J-004211;2,3,5,6-Tetrafluoro-1,4-phenylenediamine, >/=98%;ETHYL-2-TRIFLUOROMETHYL-4-METHYL-5-PYRIMIDINECARBOXYLATE

Chemical Property of 1,4-Benzenediamine, 2,3,5,6-tetrafluoro-

Chemical Property:

• Vapor Pressure: 0.167mmHg at 25°C
• Melting Point: 145 °C
• Boiling Point: 213.1°Cat760mmHg
• PKA: 1.34±0.10(Predicted)
• Flash Point: 90.5°C
• PSA: 52.04000
• Density: 1.624g/cm³
• LogP: 2.56980
• Solubility.: soluble in Methanol
• XLogP3: 1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 0
• Exact Mass: 180.03106078
• Heavy Atom Count: 12
• Complexity: 134

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,4,5,6-Tetrafluorophenylene-1,3-diamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C,Xi,Xn
• Hazard Codes: C,Xi,Xn

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1(=C(C(=C(C(=C1F)F)N)F)F)N
• Uses: 2,3,5,6-Tetrafluoro-1,4-phenylenediamine is a polyimide used in the preparation of high-performance transparent polyimide films.

Technology Process of 1,4-Benzenediamine, 2,3,5,6-tetrafluoro-

There total 14 articles about 1,4-Benzenediamine, 2,3,5,6-tetrafluoro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

4-azido-1-nitro-2,3,5,6-tetrafluorobenzene (69173-92-8) → 2,3,5,6-tetrafluorobenzene-1,4-diamine (1198-64-7)

Guidance literature:

With hydrogenchloride; tin; In ethanol; for 4h; Heating;

DOI:10.1021/jo000402p

Reference yield: 63.0%

2,3,5,6-tetrafluoro-4-nitroaniline (776-16-9) → 2,3,5,6-tetrafluorobenzene-1,4-diamine (1198-64-7)

Guidance literature:

With hydrogenchloride; tin(ll) chloride; In ethanol; for 0.5h; Heating;

DOI:10.1016/S0022-1139(96)03517-8

Reference yield: 43.0%

Hexafluorobenzene (392-56-3) → 2,3,5,6-tetrafluorobenzene-1,4-diamine (1198-64-7) + 2,4,5,6-tetrafluorobenzene-1,3-diamine (1198-63-6)

Guidance literature:

With ammonium hydroxide; at 200 ℃; for 6h;

DOI:10.1007/s11172-007-0351-2

upstream raw materials:

1,4-dihydrazino-tetrafluorobenzene

2,3,5,6-tetrafluoro-4-nitroaniline

4-azido-1-nitro-2,3,5,6-tetrafluorobenzene

2,3,4,5,6-pentafluoroaniline

Downstream raw materials:

N,N'-(2,3,5,6-tetrafluoro-1,4-phenylene)bis(4-fluorobenzenesulfonamide)

N,N'-(2,3,5,6-tetrafluoro-1,4-phenylene)bis(4-bromobenzenesulfonamide)

C₆H₄F₄N₂*C₁₂H₂₄O₆

tetrafluoro-1,4-phenylene diisocyanate

Refernces

• 1、 Vaganova,Kusov,Rodionov,Shundrina,Malykhin. "Selective mono-and diamination of polyfluorinated benzenes and pyridines with liquid ammonia". . p. 2239 - 2246. Retrieved 2008/09/20.
• 2、 Chehade, Kareem A. H.,Spielmann, H. Peter. "Facile and Efficient Synthesis of 4-Azidotetrafluoroaniline: A New Photoaffinity Reagent". . p. 4949 - 4953. Retrieved 2007/10/03.