2-{2-[2-(2-Hydroxyethoxy)phenoxy]ethoxy}phenol

Base Information

Chemical Name:2-{2-[2-(2-Hydroxyethoxy)phenoxy]ethoxy}phenol
CAS No.:65659-47-4
Molecular Formula:C16H18O5
Molecular Weight:290.316
Hs Code.:
DSSTox Substance ID:DTXSID50555772
Wikidata:Q82437182

Synonyms:65659-47-4;2-{2-[2-(2-Hydroxyethoxy)phenoxy]ethoxy}phenol;DTXSID50555772

Suppliers and Price of 2-{2-[2-(2-Hydroxyethoxy)phenoxy]ethoxy}phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-{2-[2-(2-Hydroxyethoxy)phenoxy]ethoxy}phenol

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:290.11542367
Heavy Atom Count:21
Complexity:273

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)O)OCCOC2=CC=CC=C2OCCO

Technology Process of 2-{2-[2-(2-Hydroxyethoxy)phenoxy]ethoxy}phenol

There total 7 articles about 2-{2-[2-(2-Hydroxyethoxy)phenoxy]ethoxy}phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4792-78-3
2-(2-hydroxy-phenoxy)-ethanol

: 65659-47-4
2-<2-<2-(2-hydroxyphenoxy)ethoxy>phenoxy>ethanol

Guidance literature:: Multi-step reaction with 2 steps

1: 61 percent / pyridine / 40 h / Ambient temperature

2: 1.) NaH, 2.) KOH / 1.) DMF, 80-90 deg C, 18 h, 2.) H₂O, EtOH, reflux, 1 h

With pyridine; potassium hydroxide; sodium hydride;
DOI:10.1246/bcsj.61.2047

Reference yield:

: 91300-54-8
2-(2-hydroxyethoxy)phenol ditosylate

: 65659-47-4
2-<2-<2-(2-hydroxyphenoxy)ethoxy>phenoxy>ethanol

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / dimethylformamide / 80 °C

2: alkaline hydrolysis and acidification

With sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1039/c39850001468

Reference yield:

: 120-80-9,19481-10-8,37349-32-9
benzene-1,2-diol

: 65659-47-4
2-<2-<2-(2-hydroxyphenoxy)ethoxy>phenoxy>ethanol

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / tetrabutylammonium iodide / 1 h / 160 °C

2: 1.) NaH, 2.) KOH / 1.) DMF, 80-90 deg C, 18 h, 2.) H₂O, EtOH, reflux, 1 h

With potassium hydroxide; tetra-(n-butyl)ammonium iodide; sodium hydride;
DOI:10.1246/bcsj.61.2047