5-hydroxy-6-methoxy-2-indolylcarboxylic acid

Base Information

Chemical Name:5-hydroxy-6-methoxy-2-indolylcarboxylic acid
CAS No.:2495-80-9
Molecular Formula:C10H9 N O4
Molecular Weight:207.186
Hs Code.:
Mol file:2495-80-9.mol

Synonyms:Indole-2-carboxylicacid, 5-hydroxy-6-methoxy- (7CI,8CI); 5-Hydroxy-6-methoxyindole-2-carboxylicacid; 5-Hydroxy-6-methoxyindolyl-2-carboxylic acid

Suppliers and Price of 5-hydroxy-6-methoxy-2-indolylcarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Hydroxy-6-methoxyindole-carboxylicAcid
50mg
$ 175.00

TRC
5-Hydroxy-6-methoxyindole-carboxylicAcid
10mg
$ 60.00

TRC
5-Hydroxy-6-methoxyindole-carboxylicAcid
5mg
$ 45.00

Total 4 raw suppliers

Chemical Property of 5-hydroxy-6-methoxy-2-indolylcarboxylic acid

Chemical Property:

Vapor Pressure:3.06E-11mmHg at 25°C
Boiling Point:510.4°C at 760 mmHg
Flash Point:262.5°C
PSA：82.55000
Density:1.514g/cm³
LogP:1.58030

Purity/Quality:

99% ^*data from raw suppliers

5-Hydroxy-6-methoxyindole-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-hydroxy-6-methoxy-2-indolylcarboxylic acid

There total 1 articles about 5-hydroxy-6-methoxy-2-indolylcarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 67-56-1
methanol

: C₃₆H₅₀N₂O₁₁

: 60-18-4,18875-48-4,25619-78-7,30704-25-7
L-tyrosine

: 2495-80-9
5-hydroxy-6-methoxyindole-2-carboxylic acid

Guidance literature:: With sulfuric acid; In dichloromethane; at 20 ℃; for 1h;
DOI:10.1002/anie.201806490

Reference yield: 83.0%

: C₂₀H₁₉ClN₂O₃*ClH

: 2495-80-9
5-hydroxy-6-methoxyindole-2-carboxylic acid

: 1106759-49-2
methyl (1S)-3-[(5-hydroxy-6-methoxyindol-2-yl)carbonyl]-1-chloromethyl-5-benzyloxy-1,2-dihydropyrrolo[2,3-g]indole-7-carboxylate

Guidance literature:: With sodium hydrogencarbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 23 ℃; for 2.5h;

Reference yield:

: 2495-80-9
5-hydroxy-6-methoxyindole-2-carboxylic acid

: 4-benzyloxy-8-chloromethyl-3,6,7,8-tetrahydro-3,6-diaza-as-indacene-2-carboxylic acid methyl ester

: 736138-12-8
methyl 3-[(5-hydroxy-6-methoxyindol-2-yl)carbonyl]-(1S)-(chloromethyl)-5-benzyloxy-1,2-dihydro-3H-pyrrole[3,2-e]indole-7-carboxylate

Guidance literature:: With sodium hydrogencarbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 25 ℃; for 12h;
DOI:10.1021/ja0472735