Ketone, 4-hydroxy-2,6-dimethyl-3-quinolyl phenyl

Base Information

• Chemical Name: Ketone, 4-hydroxy-2,6-dimethyl-3-quinolyl phenyl
• CAS No.: 658699-12-8
• Molecular Formula: C₁₈H₁₅NO₂
• Molecular Weight: 277.323
• Mol file: 658699-12-8.mol

Synonyms:

Chemical Property of Ketone, 4-hydroxy-2,6-dimethyl-3-quinolyl phenyl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ketone, 4-hydroxy-2,6-dimethyl-3-quinolyl phenyl

There total 1 articles about Ketone, 4-hydroxy-2,6-dimethyl-3-quinolyl phenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,6-dimethyl-quinolin-4-ol (15644-82-3) + benzoyl chloride (98-88-4) → (4-hydroxy-2,6-dimethyl-[3]quinolyl)-phenyl ketone (658699-12-8)

Guidance literature:

With aluminium trichloride; at 160 ℃;

Reference yield: 80.0%

(4-hydroxy-2,6-dimethyl-[3]quinolyl)-phenyl ketone (658699-12-8) + 6-bromo-3-(2-bromoacetyl)-2H-chromen-2-one (106578-01-2) → 6-bromo-3-(4,8-dimethyl-3-phenyl-furo[3,2-c]quinoline-2-carbonyl)-chromen-2-one

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; for 0.0666667h; microwave irradiation;

Reference yield: 75.0%

(4-hydroxy-2,6-dimethyl-[3]quinolyl)-phenyl ketone (658699-12-8) + 3-(2-bromoacetyl)-6-nitro-2H-chromen-2-one → 6-nitro-3-(4,8-dimethyl-3-phenyl-furo[3,2-c]quinoline-2-carbonyl)-chromen-2-one

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; for 0.0883333h; microwave irradiation;

upstream raw materials:

2,6-dimethyl-quinolin-4-ol

benzoyl chloride