1,2-Cyclohexanediol, 1,2-diphenyl-

Base Information

• Chemical Name: 1,2-Cyclohexanediol, 1,2-diphenyl-
• CAS No.: 65926-98-9
• Molecular Formula: C₁₈H₂₀O₂
• Molecular Weight: 268.356
• DSSTox Substance ID: DTXSID90448159
• Mol file: 65926-98-9.mol

Synonyms:1,2-Cyclohexanediol, 1,2-diphenyl-;65926-98-9;SCHEMBL9618251;DTXSID90448159

Chemical Property of 1,2-Cyclohexanediol, 1,2-diphenyl-

Chemical Property:

• XLogP3: 2.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 268.146329876
• Heavy Atom Count: 20
• Complexity: 285

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(C(C1)(C2=CC=CC=C2)O)(C3=CC=CC=C3)O

Technology Process of 1,2-Cyclohexanediol, 1,2-diphenyl-

There total 13 articles about 1,2-Cyclohexanediol, 1,2-diphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2-hydroxy-2-phenylcyclohexanone (4829-02-1) + phenylmagnesium bromide (100-58-3) → trans-1,2-Diphenylcyclohexane-1,2-diol (65926-98-9,72930-73-5,72930-74-6,134875-74-4,135211-25-5)

Guidance literature:

With cerium(III) chloride; In tetrahydrofuran; at 0 - 20 ℃; for 13h;

DOI:10.1055/s-1997-970

Reference yield: 32.0%

1,4-dibenzoylbutane (3375-38-0) → 1,2-diphenyl-1,2-cyclohexanediol (65926-98-9)

Guidance literature:

With samarium diiodide; In tetrahydrofuran; for 0.0333333h; Ambient temperature;

DOI:10.1016/0022-328X(83)85053-0

Reference yield: 19.0%

1,4-dibenzoylbutane (3375-38-0) → 1,2-diphenylcyclohex-1-ene (41317-87-7) + 1,2-diphenyl-1,2-cyclohexanediol (65926-98-9)

Guidance literature:

With titanium(III) chloride; zinc; In 1,2-dimethoxyethane; for 3.5h; Heating;

DOI:10.1021/jo00097a024

upstream raw materials:

1,4-dibenzoylbutane

(S)-(+)-2-hydroxy-2-phenylcyclohexanone

phenyllithium

2-hydroxy-2-phenylcyclohexanone

Downstream raw materials:

cis-1,2-Diphenylcyclohexane-1,2-diol

1,4-dibenzoylbutane