Acetamide, 2-((7-amino(1,2,4)triazolo(1,5-c)pyrimidin-5-yl)thio)-N,N-dimethyl-

Base Information

• Chemical Name: Acetamide, 2-((7-amino(1,2,4)triazolo(1,5-c)pyrimidin-5-yl)thio)-N,N-dimethyl-
• CAS No.: 143212-83-3
• Molecular Formula: C₉H₁₂N₆OS
• Molecular Weight: 252.3
• DSSTox Substance ID: DTXSID60162355
• Nikkaji Number: J503.314D
• Wikidata: Q83031008
• Mol file: 143212-83-3.mol

Synonyms:143212-83-3;BRN 5822090;Acetamide, 2-((7-amino(1,2,4)triazolo(1,5-c)pyrimidin-5-yl)thio)-N,N-dimethyl-;(7-Amino-s-triazolo(1,5-c)pyrimidyl-5)thioacetic acid dimethylamide;2-((7-Amino(1,2,4)triazolo(1,5-c)pyrimidin-5-yl)thio)-N,N-dimethylacetamide;2-[(7-amino-[1,2,4]triazolo[1,5-c]pyrimidin-5-yl)sulfanyl]-N,N-dimethylacetamide;Acetamide, 2-((7-amino(1,2,4)triazolo(1,5-c)pyrimidin-5-yl)thio)-N,N-d imethyl-;2-[(7-amino[1,2,4]triazolo[1,5-c]pyrimidin-5-yl)thio]-N,N-dimethylacetamide;DTXSID60162355;C9-H12-N6-O-S;STL446448;AKOS005221730;LS-8106;ACETAMIDE,2-((7-AMINO[1,2,4]TRIAZOLO(1,5-C)PYRIMIDIN-5-YL)THIO)-N,N-D IMETHYL-;2-[(7-amino[1,2,4]triazolo[1,5-c]pyrimidin-5-yl)sulfanyl]-N,N-dimethylacetamide

Chemical Property of Acetamide, 2-((7-amino(1,2,4)triazolo(1,5-c)pyrimidin-5-yl)thio)-N,N-dimethyl-

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 114.71000
• Density: 1.54g/cm³
• LogP: 0.46800
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 252.07933020
• Heavy Atom Count: 17
• Complexity: 289

Purity/Quality:

ACETAMIDE, 2-((7-AMINO(1,2,4)TRIAZOLO(1,5-C)PYRIMIDIN-5-YL)THIO)-N,N-D IMETHYL- 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C(=O)CSC1=NC(=CC2=NC=NN21)N

Technology Process of Acetamide, 2-((7-amino(1,2,4)triazolo(1,5-c)pyrimidin-5-yl)thio)-N,N-dimethyl-

There total 3 articles about Acetamide, 2-((7-amino(1,2,4)triazolo(1,5-c)pyrimidin-5-yl)thio)-N,N-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

ethyl (7-amino-s-triazole<1,5-c>pyrimidyl-5)thioacetate (143212-80-0) + dimethyl amine (124-40-3) → (7-amino-s-triazole<1,5-c>yrimidyl-5)thioacetic acid dimethylamide (143212-83-3)

Guidance literature:

In water; for 0.0833333h; Ambient temperature;

DOI:10.1007/BF00766451

Reference yield: 65.0%

methyl (7-amino-s-triazole<1,5-c>pyrimidyl-5)thioacetate (143212-79-7) + dimethyl amine (124-40-3) → (7-amino-s-triazole<1,5-c>yrimidyl-5)thioacetic acid dimethylamide (143212-83-3)

Guidance literature:

In water; for 0.0833333h; Ambient temperature;

DOI:10.1007/BF00766451

Reference yield:

7-Amino<1,2,4>triazolo<1,5-c>pyrimidine-5(6H)-thione (70182-88-6) → (7-amino-s-triazole<1,5-c>yrimidyl-5)thioacetic acid dimethylamide (143212-83-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 75 percent / MeONa / methanol / 3 h / Heating

2: 65 percent / H₂O / 0.08 h / Ambient temperature

With sodium methylate; In methanol; water;

DOI:10.1007/BF00766451

upstream raw materials:

ethyl (7-amino-s-triazole<1,5-c>pyrimidyl-5)thioacetate

dimethyl amine

methyl (7-amino-s-triazole<1,5-c>pyrimidyl-5)thioacetate

7-Amino<1,2,4>triazolo<1,5-c>pyrimidine-5(6H)-thione

Refernces