Syringetin

Base Information

• Chemical Name: Syringetin
• CAS No.: 4423-37-4
• Molecular Formula: C17H14O8
• Molecular Weight: 346.293
• Hs Code.: 2914509090
• UNII: J68JG79B9W
• ChEMBL ID: CHEMBL489142
• DSSTox Substance ID: DTXSID60196074
• Metabolomics Workbench ID: 25581
• Nikkaji Number: J13.513E
• Wikidata: Q3509026
• Wikipedia: Syringetin
• Mol file: 4423-37-4.mol

Synonyms:3,5,7,4'-tetrahydroxy-3',5'dimethoxyflavone;syringetin

Chemical Property of Syringetin

Chemical Property:

• Vapor Pressure: 4.38E-16mmHg at 25°C
• Melting Point: 287-289oC
• Boiling Point: 622.4°Cat760mmHg
• PKA: 6.29±0.40(Predicted)
• Flash Point: 231.9°C
• PSA: 129.59000
• Density: 1.591g/cm³
• LogP: 2.29960
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 3
• Exact Mass: 346.06886740
• Heavy Atom Count: 25
• Complexity: 533

Purity/Quality:

98%Min ^*data from raw suppliers

Syringetin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=CC(=C1O)OC)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O

Technology Process of Syringetin

There total 3 articles about Syringetin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

syringetin-3-O-β-D-galactopyranoside (40039-49-4,55025-56-4) → D-Galactose (10257-28-0) + syringetin (4423-37-4)

Guidance literature:

With oxonium; Product distribution;

DOI:10.1016/0031-9422(88)80719-2

Reference yield:

myricetin (529-44-2) + S-adenosyl-L-methionine (485-80-3,15519-60-5,60018-85-1,60018-86-2,79845-28-6) → syringetin (4423-37-4)

Guidance literature:

With Citrus reticulata O-methyltransferase gene-pET₃₂a recombinant; In aq. buffer; at 37 ℃; for 2h; pH=8; Kinetics; Enzymatic reaction;

DOI:10.3390/molecules25040858

Reference yield:

→ syringetin (4423-37-4)

Guidance literature:

With hydrogenchloride; ethanol;

upstream raw materials:

syringetin-3-O-β-D-galactopyranoside

myricetin

S-adenosyl-L-methionine

Downstream raw materials:

chrysin-7-glucuronide on cytochrome

Refernces

• 1、 Yasukawa, Ken,Takido, Michio. "QUERCETIN 3-RHAMNOSYL (1->2) GALACTOSIDE FROM LYSIMACHIA VULGARIS VAR DAVURICA". . p. 3017 - 3018. Retrieved 2007/10/02.