N4,N6-dimethylpyrimidine-4,6-diamine

Base Information

Chemical Name:N4,N6-dimethylpyrimidine-4,6-diamine
CAS No.:66131-72-4
Molecular Formula:C6H10N4
Molecular Weight:138.17000
Hs Code.:
DSSTox Substance ID:DTXSID40559709
Nikkaji Number:J2.871.506D

Synonyms:66131-72-4;N4,N6-dimethylpyrimidine-4,6-diamine;4-N,6-N-dimethylpyrimidine-4,6-diamine;4,6-Pyrimidinediamine, N,N'-dimethyl-;4,6-dimethylamino-pyrimidine;SCHEMBL5563364;DTXSID40559709;AKOS006359470;4,6-Pyrimidinediamine,N,N-dimethyl-(9ci);CS-0248179;N~4~,N~6~-Dimethylpyrimidine-4,6-diamine;EN300-392997;F8884-8151

Suppliers and Price of N4,N6-dimethylpyrimidine-4,6-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of N4,N6-dimethylpyrimidine-4,6-diamine

Chemical Property:

PSA：55.04000
LogP:0.70600
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:138.090546336
Heavy Atom Count:10
Complexity:85.7

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNC1=CC(=NC=N1)NC
Uses Piperidine is the most common nitrogen heterocycle in FDA-approved pharmaceuticals and thus represents a key structure in drug discovery.Piperidine is the most common nitrogen heterocycle in FDA-approved pharmaceuticals and thus represents a key structure in drug discovery.

Technology Process of N4,N6-dimethylpyrimidine-4,6-diamine

There total 1 articles about N4,N6-dimethylpyrimidine-4,6-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1193-21-1
4,6-dichloropyrimidine

: 74-89-5
methylamine

: 66131-72-4
4,6-bis-(methylamino)pyrimidine

Guidance literature:: In water; at 150 ℃; for 12h; Autoclave;
DOI:10.1021/jo902245q

Reference yield: 51.0%

: 1206706-17-3
C₂₈H₂₄Cl₂N₈O₂

: 66131-72-4
4,6-bis-(methylamino)pyrimidine

: 1206706-31-1
C₃₄H₃₂N₁₂O₂

Guidance literature:: 4,6-bis-(methylamino)pyrimidine; With sodium hydride; In tetrahydrofuran; at 20 ℃; Reflux;

C₂₈H₂₄Cl₂N₈O₂; In tetrahydrofuran; toluene; for 8h; Reflux;
DOI:10.1021/jo902245q