L-Tyrosine, O-ethyl-N-[(phenylmethoxy)carbonyl]-

Base Information

Chemical Name:L-Tyrosine, O-ethyl-N-[(phenylmethoxy)carbonyl]-
CAS No.:66147-90-8
Molecular Formula:C19H21NO5
Molecular Weight:343.379
Hs Code.:
DSSTox Substance ID:DTXSID60444188
Wikidata:Q82262242

Synonyms:L-Tyrosine, O-ethyl-N-[(phenylmethoxy)carbonyl]-;66147-90-8;DTXSID60444188

Suppliers and Price of L-Tyrosine, O-ethyl-N-[(phenylmethoxy)carbonyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of L-Tyrosine, O-ethyl-N-[(phenylmethoxy)carbonyl]-

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:343.14197277
Heavy Atom Count:25
Complexity:414

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=CC=C(C=C1)CC(C(=O)O)NC(=O)OCC2=CC=CC=C2
Isomeric SMILES:CCOC1=CC=C(C=C1)C[C@@H](C(=O)O)NC(=O)OCC2=CC=CC=C2

Technology Process of L-Tyrosine, O-ethyl-N-[(phenylmethoxy)carbonyl]-

There total 4 articles about L-Tyrosine, O-ethyl-N-[(phenylmethoxy)carbonyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (S)-2-Benzyloxycarbonylamino-3-(4-ethoxy-phenyl)-propionic acid ethyl ester

: 66147-90-8
(2S)-2-[(benzyloxycarbonyl)amino]-3-(4-ethoxyphenyl)propanoic acid

Guidance literature:: With sodium hydroxide; In methanol; for 0.5h; Yield given;
DOI:10.1021/jo00322a049

Reference yield:

: 1164-16-5
Z-L-Tyr-OH

: 66147-90-8
(2S)-2-[(benzyloxycarbonyl)amino]-3-(4-ethoxyphenyl)propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃, 18-crown-6 / benzene / 1.5 h / Heating

2: NaOH / methanol / 0.5 h

With sodium hydroxide; 18-crown-6 ether; potassium carbonate; In methanol; benzene;
DOI:10.1021/jo00322a049

Reference yield:

: 74-96-4
ethyl bromide

: 1164-16-5
Z-L-Tyr-OH

: 66147-90-8
(2S)-2-[(benzyloxycarbonyl)amino]-3-(4-ethoxyphenyl)propanoic acid

Guidance literature:: With sodium hydride; Yield given. Multistep reaction; 1.) DMF, 1 h, 10 deg C, 2.) 3.5 h, 10 deg C;
DOI:10.1021/jo00170a056