2-Anilinoethyl(phenyl)formamide

Base Information

• Chemical Name: 2-Anilinoethyl(phenyl)formamide
• CAS No.: 55055-34-0
• Molecular Formula: C15H16N2O
• Molecular Weight: 240.305
• NSC Number: 122358
• DSSTox Substance ID: DTXSID20970413
• Wikidata: Q82953593
• ChEMBL ID: CHEMBL1880369
• Mol file: 55055-34-0.mol

Synonyms:2-Anilinoethyl(phenyl)formamide;NSC122358;55055-34-0;MLS002707208;NSC 122358;N-(2-anilinoethyl)-N-phenylformamide;CHEMBL1880369;DTXSID20970413;N-(2-anilinoethyl)-N-phenyl-formamide;NSC-122358;SMR001574602

Chemical Property of 2-Anilinoethyl(phenyl)formamide

Chemical Property:

• Vapor Pressure: 3.72E-08mmHg at 25°C
• Boiling Point: 446.2°Cat760mmHg
• Flash Point: 223.6°C
• Density: 1.171g/cm³
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 240.126263138
• Heavy Atom Count: 18
• Complexity: 233

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)NCCN(C=O)C2=CC=CC=C2

Technology Process of 2-Anilinoethyl(phenyl)formamide

There total 14 articles about 2-Anilinoethyl(phenyl)formamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

bis(1,3-diphenyl-2-imidazolidinylidene) (2179-89-7) → 1,3-diphenyl-2-imidazolidone (728-24-5) + N-formyl-N,N'-diphenylethylenediamine (55055-34-0) + 1,2,5,8-Tetraphenyl-[1,2,5,8]tetrazecane-6,7-dione (87443-00-3) + N,N'-diphenylethylenediamine (150-61-8)

Guidance literature:

With air; 9,10-Dibromoanthracene; In chloroform; further solvents: dichlorometane, acetonitrile, same reaction without fluorescer;

DOI:10.1016/S0040-4039(00)81910-3

Reference yield: 63.0%

N,N'-diphenylethylenediamine (150-61-8) + (S)-5,5-Dimethyl-2-((R)-phenethylcarbamoyl-phenylacetylamino-methyl)-thiazolidine-4-carboxylic acid → 3,3-dimethyl-D-cysteine (52-67-5) + N-formyl-N,N'-diphenylethylenediamine (55055-34-0) + phenaceturic acid α-phenethylamide (102016-26-2)

Guidance literature:

In acetic acid; Heating;

DOI:10.3987/COM-88-4651

Reference yield: 49.0%

Penicillin G potassium (113-98-4) + N,N'-diphenylethylenediamine (150-61-8) → 3,3-dimethyl-D-cysteine (52-67-5) + N-(2-anilinoethyl)phenylacetanilide (59281-89-9) + N-formyl-N,N'-diphenylethylenediamine (55055-34-0) + 6,7-dihydro-6H-3-phenylacetylamino-1,5-diazepin-2-one

Guidance literature:

In water; acetic acid; for 6h; Further byproducts given; Heating;

DOI:10.3987/COM-88-4651

upstream raw materials:

formic acid

N,N'-diphenylethylenediamine

bis(1,3-diphenyl-2-imidazolidinylidene)

(1,3-Diphenylimidazolidin-2-yl)-diazoessigsaeure-methylester

Downstream raw materials:

1,3-diphenyl-2-imidazolidinethione

4,5-Dihydro-1,3-diphenyl-1H-imidazoliumchlorid

1,3-diphenyl-2-imidazolinium triflate