Cytochlor

Base Information

Chemical Name:Cytochlor
CAS No.:32387-56-7
Molecular Formula:C₉H₁₂ClN₃O₄
Molecular Weight:261.665
Hs Code.:
UNII:J14D49ZN55
DSSTox Substance ID:DTXSID40186099
Nikkaji Number:J1.228.514K
Wikidata:Q27281010
NCI Thesaurus Code:C28950
Metabolomics Workbench ID:153378
ChEMBL ID:CHEMBL4297275
Mol file:32387-56-7.mol

Synonyms:2'-deoxy-5-chlorocytidine;5-chloro-2'-deoxycytidine;5-chlorodeoxycytidine

Suppliers and Price of Cytochlor

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Cytochlor
5mg
$ 409.00

TRC
5-Chloro-2’-deoxycytidine
50mg
$ 900.00

Biosynth Carbosynth
5-Chloro-2'-deoxycytidine
100 mg
$ 950.00

Biosynth Carbosynth
5-Chloro-2'-deoxycytidine
10 mg
$ 190.00

Biosynth Carbosynth
5-Chloro-2'-deoxycytidine
5 mg
$ 120.00

Biosynth Carbosynth
5-Chloro-2'-deoxycytidine
50 mg
$ 600.00

American Custom Chemicals Corporation
5-CHLORO-2'-DEOXYCYTIDINE 95.00%
25MG
$ 469.35

Total 12 raw suppliers

Chemical Property of Cytochlor

Chemical Property:

Boiling Point:497.9°Cat760mmHg
Flash Point:254.9°C
PSA：110.60000
Density:1.86g/cm³
LogP:-0.29920
Storage Temp.:2-8°C
XLogP3:-0.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:261.0516336
Heavy Atom Count:17
Complexity:398

Purity/Quality:

99% ^*data from raw suppliers

Cytochlor ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(OC1N2C=C(C(=NC2=O)N)Cl)CO)O
Isomeric SMILES:C1[C@@H]([C@H](O[C@H]1N2C=C(C(=NC2=O)N)Cl)CO)O
Recent ClinicalTrials:Cytochlor and Tetrahydrouridine as Radiosensitizers and Cisplatin Combined With Radiation Therapy in Treating Patients With Advanced Squamous Cell Carcinoma of the Oral Cavity (Mouth) or Oropharynx (Throat)
Uses 5-Chloro-2’-deoxycytidine is a good markers to detect myeloperoxidase (MPO) activity in biological fluids. Possible radiosensitizing agent for cancer treatment.

Technology Process of Cytochlor

There total 1 articles about Cytochlor which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 951-77-9
2'-Deoxycytidine

: 32387-56-7
5-chloro-2′-deoxycytidine

Guidance literature:: With N-chloro-succinimide; 1-ethylene glycol monomethyl ether-3-methylimidazolium methanesulfonate; at 50 ℃; for 1h;
DOI:10.1055/s-0029-1217042

Reference yield:

: 32387-56-7
5-chloro-2′-deoxycytidine

: 1356140-66-3
4-N-acetyl-5-chloro-5'-O-(4,4'-dimethoxytrityl)-deoxycytidine

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 9 h / 45 °C

2: pyridine / 5 h / 20 °C

With pyridine; In N,N-dimethyl-formamide;
DOI:10.1039/c1ob06411h

Reference yield:

: 32387-56-7
5-chloro-2′-deoxycytidine

: 1356140-67-4
4-N-acetyl-5-chloro-5'-O-(4,4'-dimethoxytrityl)-deoxycytidine 3'-(2-cyanoethyl N,N-diisopropylphosphoramidite)

Guidance literature:: Multi-step reaction with 3 steps

1: N,N-dimethyl-formamide / 9 h / 45 °C

2: pyridine / 5 h / 20 °C

3: 1H-tetrazole; diisopropylamine / dichloromethane / 5 h / 20 °C / Inert atmosphere

With pyridine; 1H-tetrazole; diisopropylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/c1ob06411h