N-[(cyclohexylamino)-phenylphosphoryl]cyclohexanamine

Base Information

• Chemical Name: N-[(cyclohexylamino)-phenylphosphoryl]cyclohexanamine
• CAS No.: 14612-96-5
• Molecular Formula: C18H29 N2 O P
• Molecular Weight: 320.415
• NSC Number: 203264
• DSSTox Substance ID: DTXSID70308368
• Wikidata: Q82056216
• Mol file: 14612-96-5.mol

Synonyms:14612-96-5;N-[(cyclohexylamino)-phenylphosphoryl]cyclohexanamine;NSC203264;DTXSID70308368;Phenyl dicyclohexyl diamidophosphonate;NSC-203264;Phosphonic diamide,N'-dicyclohexyl-P-phenyl-

Chemical Property of N-[(cyclohexylamino)-phenylphosphoryl]cyclohexanamine

Chemical Property:

• Boiling Point: 448°Cat760mmHg
• Flash Point: 224.7°C
• Density: 1.09g/cm³
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 320.20175055
• Heavy Atom Count: 22
• Complexity: 345

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(CC1)NP(=O)(C2=CC=CC=C2)NC3CCCCC3

Technology Process of N-[(cyclohexylamino)-phenylphosphoryl]cyclohexanamine

There total 2 articles about N-[(cyclohexylamino)-phenylphosphoryl]cyclohexanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

P,P-dichlorophenylphosphine oxide (824-72-6) + cyclohexylamine (108-91-8,157973-60-9) → Bis(cyclohexylamino)phenylphosphine oxide (14612-96-5)

Guidance literature:

In neat (no solvent); at 20 ℃; for 0.0833333h; Sonication; Green chemistry;

DOI:10.1080/10426507.2020.1854254

Reference yield:

→ Bis(cyclohexylamino)phenylphosphine oxide (14612-96-5)

Guidance literature:

Phenylphosphoroxydichlorid, Cyclohexylamin, CCl4/Bzl.;

DOI:10.1007/BF00929555

Reference yield: 44.0%

Bis(cyclohexylamino)phenylphosphine oxide (14612-96-5) + dimethyltin dichloride (753-73-1) → C18H29N2OP*Sn(4+)*2Cl(1-)*2CH3(1-)

Guidance literature:

In methanol; at 20 ℃; under 760.051 Torr; Sonication;

DOI:10.1002/aoc.3875

upstream raw materials:

P,P-dichlorophenylphosphine oxide

cyclohexylamine

Refernces

• 1、 Bouchareb, Fouzia,Berredjem, Malika,Bouzina, Abdeslem,Guerfi, Meriem. "Ultrasound-promoted, rapid and green synthesis of phosphonamide derivatives under catalyst and solvent-free conditions". . p. 422 - 430. Retrieved 2020/12/15.