6-Phenylfuro[2,3-b]pyrazine

Base Information

Chemical Name:6-Phenylfuro[2,3-b]pyrazine
CAS No.:66479-90-1
Molecular Formula:C12H8N2O
Molecular Weight:196.208
Hs Code.:
DSSTox Substance ID:DTXSID70496991
Nikkaji Number:J3.665.075C

Synonyms:6-Phenylfuro[2,3-b]pyrazine;66479-90-1;6-Phenyl-furo[2,3-b]pyrazine;DTXSID70496991

Suppliers and Price of 6-Phenylfuro[2,3-b]pyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 6-Phenylfuro[2,3-b]pyrazine

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:196.063662883
Heavy Atom Count:15
Complexity:216

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC3=NC=CN=C3O2

Technology Process of 6-Phenylfuro[2,3-b]pyrazine

There total 4 articles about 6-Phenylfuro[2,3-b]pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 2-(3-chloropyrazin-2-yl)-1-phenylethanone

: 66479-90-1
2-Phenylfuro<2,3-b>pyrazine

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 140 ℃; for 3h;
DOI:10.1016/j.tet.2006.08.018

Reference yield: 76.0%

: 1439396-18-5
2-chloro-3-(phenylethynyl)pyrazine

: 66479-90-1
2-Phenylfuro<2,3-b>pyrazine

Guidance literature:: With potassium carbonate; In water; dimethyl sulfoxide; at 80 ℃; for 1h;
DOI:10.1039/c3ob41069b

Reference yield:

: 536-74-3
phenylacetylene

: 66479-90-1
2-Phenylfuro<2,3-b>pyrazine

Guidance literature:: Multi-step reaction with 2 steps

1.1: palladium 10% on activated carbon; copper(l) iodide; triphenylphosphine; triethylamine / ethanol / 0.25 h

1.2: 2 h / 60 °C / Inert atmosphere

2.1: potassium carbonate / dimethyl sulfoxide; water / 1 h / 80 °C

With copper(l) iodide; palladium 10% on activated carbon; potassium carbonate; triethylamine; triphenylphosphine; In ethanol; water; dimethyl sulfoxide;
DOI:10.1039/c3ob41069b