7-Iodo-3,4-dihydroisoquinolin-1(2H)-one

Base Information

Chemical Name:7-Iodo-3,4-dihydroisoquinolin-1(2H)-one
CAS No.:66491-04-1
Molecular Formula:C9H8INO
Molecular Weight:273.07000
Hs Code.:
DSSTox Substance ID:DTXSID20441517
Nikkaji Number:J3.363.638E

Synonyms:7-Iodo-3,4-dihydroisoquinolin-1(2H)-one;66491-04-1;7-iodo-3,4-dihydro-2H-isoquinolin-1-one;1(2H)-Isoquinolinone, 3,4-dihydro-7-iodo-;SCHEMBL793665;SCHEMBL11619994;DTXSID20441517;FEFKPAJGQXKUKJ-UHFFFAOYSA-N;AKOS016000979;7-Iodo-3,4-dihydroisoquinoline-1(2H)-one;CS-0326703;F52967

Suppliers and Price of 7-Iodo-3,4-dihydroisoquinolin-1(2H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
7-Iodo-3,4-dihydroisoquinolin-1(2H)-one 95+%
1g
$ 620.00

Chemenu
7-Iodo-3,4-dihydroisoquinolin-1(2H)-one 95%
1g
$ 580.00

American Custom Chemicals Corporation
7-IODO-3,4-DIHYDROISOQUINOLIN-1(2H)-ONE 95.00%
1G
$ 1309.35

American Custom Chemicals Corporation
7-IODO-3,4-DIHYDROISOQUINOLIN-1(2H)-ONE 95.00%
5MG
$ 496.45

Alichem
7-Iodo-3,4-dihydroisoquinolin-1(2H)-one
25g
$ 3333.00

Alichem
7-Iodo-3,4-dihydroisoquinolin-1(2H)-one
10g
$ 2000.00

Alichem
7-Iodo-3,4-dihydroisoquinolin-1(2H)-one
5g
$ 1466.30

AK Scientific
7-Iodo-3,4-dihydroisoquinolin-1(2H)-one
25g
$ 10985.00

Total 9 raw suppliers

Chemical Property of 7-Iodo-3,4-dihydroisoquinolin-1(2H)-one

Chemical Property:

PSA：32.59000
LogP:1.58750
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:272.96506
Heavy Atom Count:12
Complexity:195

Purity/Quality:

95+% ^*data from raw suppliers

7-Iodo-3,4-dihydroisoquinolin-1(2H)-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CNC(=O)C2=C1C=CC(=C2)I

Technology Process of 7-Iodo-3,4-dihydroisoquinolin-1(2H)-one

There total 12 articles about 7-Iodo-3,4-dihydroisoquinolin-1(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: methyl 2-(((4-iodophenethyl)carbamoyl)oxy)benzoate

: 66491-04-1
7-iodo-3,4-dihydro-1(1H)-isoquinolinone

Guidance literature:: With trifluorormethanesulfonic acid; In dichloromethane; at 0 - 20 ℃; for 1h; Inert atmosphere;
DOI:10.1002/chem.201402447

Reference yield:

: 66491-03-0
7-amino-3,4-dihydroisoquinoline-1(2H)-one

: 66491-04-1
7-iodo-3,4-dihydro-1(1H)-isoquinolinone

Guidance literature:: With hydrogenchloride; potassium iodide; sodium nitrite; In water;
DOI:10.1021/jm9604787

Reference yield:

: 7681-65-4
copper(l) iodide

: 66491-03-0
7-amino-3,4-dihydroisoquinoline-1(2H)-one

: 66491-04-1
7-iodo-3,4-dihydro-1(1H)-isoquinolinone

Guidance literature:: copper(l) iodide; 7-amino-3,4-dihydroisoquinoline-1(2H)-one; With hydrogenchloride; sodium nitrite; In water; at 0 ℃; for 0.25h;

With copper(l) iodide; potassium iodide; In dichloromethane; water; at 20 ℃;