2-{[(methylsulfonyl)oxy]methyl}butyl methanesulfonate

Base Information

• Chemical Name: 2-{[(methylsulfonyl)oxy]methyl}butyl methanesulfonate
• CAS No.: 64923-60-0
• Molecular Formula: C₇H₁₆O₆S₂
• Molecular Weight: 260.332
• Mol file: 64923-60-0.mol

Synonyms:NSC 513150;1,3-Propanediol,2-ethyl-, dimethanesulfonate (9CI);

Chemical Property of 2-{[(methylsulfonyl)oxy]methyl}butyl methanesulfonate

Chemical Property:

• Vapor Pressure: 2.08E-08mmHg at 25°C
• Refractive Index: 1.469
• Boiling Point: 465.8°C at 760 mmHg
• Flash Point: 235.5°C
• Density: 1.306g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-{[(methylsulfonyl)oxy]methyl}butyl methanesulfonate

There total 3 articles about 2-{[(methylsulfonyl)oxy]methyl}butyl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-ethyl-1,3-propandiol (2612-29-5) + methanesulfonyl chloride (124-63-0) → 2-ethylpropane-1,3-diyl dimethanesulfonate (64923-60-0)

Guidance literature:

With pyridine; In benzene;

Reference yield:

dimethyl ethylmalonate (26717-67-9) → 2-ethylpropane-1,3-diyl dimethanesulfonate (64923-60-0)

Guidance literature:

Multi-step reaction with 2 steps

1: lithium borohydride / tetrahydrofuran / 16 h / 0 - 20 °C / Inert atmosphere

2: triethylamine / tetrahydrofuran / 0.5 h / 0 - 20 °C

With lithium borohydride; triethylamine; In tetrahydrofuran;

Reference yield:

ethyl diethyl malonate (133-13-1) → 2-ethylpropane-1,3-diyl dimethanesulfonate (64923-60-0)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄ / diethyl ether

2: Py / benzene

With pyridine; lithium aluminium tetrahydride; In diethyl ether; benzene;

upstream raw materials:

2-ethyl-1,3-propandiol

methanesulfonyl chloride

ethyl diethyl malonate

dimethyl ethylmalonate

Refernces

• 1、 -. "CHEMICAL COMPOUNDS AS INHIBITORS OF INTERLEUKIN-1 ACTIVITY". Paragraph 00882; 00884. . Retrieved 2018/08/12.