2612-29-5

Basic information

• Product Name: 2-ethylpropane-1,3-diol
• Synonyms: 2-ethylpropane-1,3-diol;2-Ethyl-1,3-propanediol;1,3-Propanediol, 2-ethyl-
• CAS NO: 2612-29-5
• Molecular Formula: C₅H₁₂O₂
• Molecular Weight: 104.14758
• EINECS: 220-038-3
• Mol File: 2612-29-5.mol
• Article Data: 32

Chemical Properties

• Melting Point: 50.86°C (estimate)
• Boiling Point: 209.24°C (rough estimate)
• Flash Point: 105.272 °C
• Appearance: /
• Density: 0.9917 (rough estimate)
• Refractive Index: 1.4470
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform, Methanol
• PKA: 14.51±0.10(Predicted)
• CAS DataBase Reference: 2-ethylpropane-1,3-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethylpropane-1,3-diol(2612-29-5)
• EPA Substance Registry System: 2-ethylpropane-1,3-diol(2612-29-5)

Safety Data

• Hazardous Substances Data: 2612-29-5(Hazardous Substances Data)

Usage

Uses

2-Ethyl-1,3-propanediol is an intermediate in the synthesis of Peloruside A related compounds, novel antimitotic agents with Paclitaxel (P132500)-like microtubule-stabilizing activity.

InChI:InChI=1/C5H12O2/c1-2-5(3-6)4-7/h5-7H,2-4H2,1H3

Upstream product

• 1462-12-0 diethyl ethylidenemalonate 
• 64-17-5 ethanol 
• 133-13-1 ethyl diethyl malonate 
• 97-93-8 triethylaluminum 
• 556-52-5 oxiranyl-methanol 
• 922-63-4 ethylacrolein 
• 26717-67-9 dimethyl ethylmalonate 
• 161449-31-6 1,3-di-O-acetyl-2-ethyl-1,3-propanediol 

Downstream Products

• 620-36-0 3-ethylglutaric acid 
• 64923-60-0 2-ethylpropane-1,3-diyl dimethanesulfonate 
• 24330-55-0 2-ethylpropane-1,3-diol di-p-toluenesulphonate 
• 4374-62-3 2-hydroxymethyl-butyric acid 
• 28148-05-2 1-Bromo-2-(bromomethyl)butane 
• 27942-82-1 5-Ethyl-2-phenyl-[1,3]dioxane 
• 14058-59-4 2-(Benzyloxymethyl)butan-1-ol 
• 443284-31-9 2-(4-methoxy-benzyloxymethyl)-butan-1-ol 
• 437985-81-4 3-{6-[diisopropyl-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)silanyloxymethyl]-4-methyl-octa-2E,4E-dienoyl}-4-hydroxy-5-[4-(2-methoxyethoxymethoxy)phenyl]-1H-pyridine-2-one 
• 437985-79-0 (4E,6E)-8-[diisopropyl-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)silanyloxymethyl]-3-hydroxy-2-{2-[4-(2-methoxyethoxymethoxy)phenyl]vinylcarbamoyl}-6-methyl-deca-2,4,6-trienoic acid ethyl ester 
• 116-53-0 2-Methylbutanoic acid 
• 3586-58-1 2-methylenebutyric acid 
• 72604-79-6 (2R)-2-(hydroxymethyl)-2-methylbutanoic acid 
• 56640-48-3 2-benzyl butanol 

Relevant articles and documents

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Synthesis of Enantiomerically Enriched 2-Hydroxymethylalkanoic Acids by Oxidative Desymmetrisation of Achiral 1,3-Diols Mediated by Acetobacter aceti

The stereoselective desymmetrisation of achiral 2-alkyl-1,3-diols is performed by oxidation of one of the two enantiotopic primary alcohol moieties by means of Acetobacter aceti MIM 2000/28 to afford the corresponding chiral 2-hydroxymethyl alkanoic acids (up to 94 % ee). The procedure, carried out in aqueous medium under mild conditions of pH, temperature and pressure, contributes to enlarge the portfolio of enzymatic oxidations available to organic chemists for the development of sustainable manufacturing processes.