Aminoprofen

Base Information

Chemical Name:Aminoprofen
CAS No.:83394-44-9
Molecular Formula:C₁₅H₂₃NO₂
Molecular Weight:249.353
Hs Code.:2924299090

Synonyms:Aminoprofen;

Suppliers and Price of Aminoprofen

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 12 raw suppliers

Chemical Property of Aminoprofen

Chemical Property:

Boiling Point:445.5°Cat760mmHg
Flash Point:223.2°C
PSA：49.33000
Density:1.029g/cm³
LogP:2.48800

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description Aminoprofen, an amide of ibuprofen, is a topical anti-arthritic with analgesic properties. It is comparable to methyl salicylate in the carrageenan-induced paw edema and croton oil ear edema models, and is reported to be a superior analgesic.

Technology Process of Aminoprofen

There total 5 articles about Aminoprofen which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 71381-91-4,114978-05-1,115588-20-0,34715-60-1
(+/-)-2-(4-isobutylphenyl)propanoyl chloride

: 141-43-5
ethanolamine

: 83394-44-9,82821-47-4
N-(2-hydroxyethyl)-2-(4-isobutylphenyl)propanamide

Guidance literature:: In dichloromethane; at 25 ℃; for 3h;
DOI:10.3109/14756366.2015.1088840

Reference yield:

: 41283-72-1
ibuprofen ethyl ester

: 141-43-5
ethanolamine

: 83394-44-9,82821-47-4
N-(2-hydroxyethyl)-2-(4-isobutylphenyl)propanamide

Guidance literature:: In dichloromethane; for 8h; Reflux;
DOI:10.1007/s00706-015-1557-x

Reference yield:

: 51146-57-7,58560-75-1
(R)-ibuprofene

: 83394-44-9,82821-47-4
N-(2-hydroxy-ethyl)-2-(4-isobutyl-phenyl)-propionamide

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / 3 h / Heating

2: 2.16 g / Et₃N / CH₂Cl₂ / 4 h

With thionyl chloride; triethylamine; In dichloromethane;
DOI:10.1021/jm049082i