1-(((2-Hydroxyphenyl)imino)methyl)-2-naphthol

Base Information

• Chemical Name: 1-(((2-Hydroxyphenyl)imino)methyl)-2-naphthol
• CAS No.: 894-93-9
• Molecular Formula: C17H13 N O2
• Molecular Weight: 263.296
• European Community (EC) Number: 212-975-1
• NSC Number: 111847
• DSSTox Substance ID: DTXSID901233809
• Nikkaji Number: J195.192K,J3.554.577H
• ChEMBL ID: CHEMBL1984884
• Mol file: 894-93-9.mol

Synonyms:HAMNO;138736-73-9;NSC111847;894-93-9;1-(((2-Hydroxyphenyl)imino)methyl)-2-naphthol;137320-35-5;2(1H)-Naphthalenone, 1-[[(2-hydroxyphenyl)amino]methylene]-;CID 6335338;(1E)-1-[(2-hydroxyanilino)methylidene]naphthalen-2-one;MLS000737724;EINECS 212-975-1;NSC 111847;NSC-111847;(1Z)-1-[(2-hydroxyanilino)methylidene]naphthalen-2-one;(E)-1-(((2-hydroxyphenyl)imino)methyl)naphthalen-2-ol;CID 5484356;1-(2-Hydroxyphenyliminomethyl)-2-naphthol;1-[(2-hydroxyphenyl)iminomethyl]naphthalen-2-ol;1-(((2-Hydroxyphenyl)imino)methyl)naphthalen-2-ol;1-[(E)-[(2-hydroxyphenyl)imino]methyl]naphthalen-2-ol;1-[[(2-HYDROXYPHENYL)IMINO]METHYL]-2-NAPHTHOL;1-(((2-Hydroxyphenyl)amino)methylene)naphthalen-2(1H)-one;1-[(1E)-[(2-HYDROXYPHENYL)IMINO]METHYL]NAPHTHALEN-2-OL;2-Naphthalenol, 1-(((2-hydroxyphenyl)imino)methyl)-;2-naphthalenol, 1-[[(2-hydroxyphenyl)imino]methyl]-;CBDivE_001328;SCHEMBL2029030;CHEMBL1984884;HAMNO (NSC111847);DTXSID901233809;HMS2851M15;BCP28955;AKOS003616134;AKOS024333479;AKOS037515567;NCGC00246720-01;BS-47360;SMR000528517;HY-111285;CS-0034826;J3.554.577H;E85104;1-[(2-hydroxyphenylimino)-methyl]naphthalen-2-ol;1-[[(2-Hydroxyphenyl)imino]methyl]-2-naphthalenol;1-[(E)-[(2-Hydroxyphenyl)imino]methyl]-2-naphthol;F0827-0108;1-((2-Hydroxyphenylamino)methylene)naphthalen-2(1H)-one

Chemical Property of 1-(((2-Hydroxyphenyl)imino)methyl)-2-naphthol

Chemical Property:

• Vapor Pressure: 3.51E-10mmHg at 25°C
• Boiling Point: 488.8°C at 760 mmHg
• Flash Point: 249.4°C
• PSA: 52.82000
• Density: 1.392g/cm³
• LogP: 4.00160
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 263.094628657
• Heavy Atom Count: 20
• Complexity: 344

Purity/Quality:

99.9% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC(=C2C=NC3=CC=CC=C3O)O

Technology Process of 1-(((2-Hydroxyphenyl)imino)methyl)-2-naphthol

There total 4 articles about 1-(((2-Hydroxyphenyl)imino)methyl)-2-naphthol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.6%

2-amino-phenol (95-55-6) + 2-hydroxynaphthalene-1-carbaldehyde (708-06-5) → 1-((2-hydroxyphenylimino)methyl)naphth-2-ol (894-93-9)

Guidance literature:

In toluene; Reflux;

DOI:10.1016/j.molstruc.2021.131322

Reference yield: 88.0%

1-((pyrimidine-2-ylimino)methyl)naphthalene-2-ol (148642-24-4) + 2-amino-phenol (95-55-6) → 1-((2-hydroxyphenylimino)methyl)naphth-2-ol (894-93-9)

Guidance literature:

With formic acid; In water; at 110 ℃; for 0.416667h;

DOI:10.2298/JSC151202064B

Reference yield:

β-naphthol (135-19-3) → 1-((2-hydroxyphenylimino)methyl)naphth-2-ol (894-93-9)

Guidance literature:

Multi-step reaction with 2 steps

1: formic acid / water / 0.25 h / 120 °C

2: formic acid / water / 0.42 h / 110 °C

With formic acid; In water;

DOI:10.2298/JSC151202064B

upstream raw materials:

2-amino-phenol

2-hydroxynaphthalene-1-carbaldehyde

β-naphthol

1-((pyrimidine-2-ylimino)methyl)naphthalene-2-ol

Downstream raw materials:

Zn⁽²⁺⁾*(C₁₀H₆(O)CHNC₆H₄O)^(2-) = Zn(C₁₀H₆(O)CHNC₆H₄O)

Refernces

• 1、 Xing, Lin,Zheng, Xiaoyu,Sun, Wenyu,Yuan, Hua,Hu, Lei,Yan, Zhengquan. "UV–vis spectral property of a multi-hydroxyl Schiff-base derivative and its colorimetric response to some special metal ions". . p. 455 - 460. Retrieved 2018.
• 2、 Yan, Zhengquan,Wang, Cong,Tang, Yulian,Zhu, Yanjie,Cao, Qianying,Yang, Tianran,Hu, Lei. "π-Conjugated molecules identified for reversible and visual detection of F? in aqueous: Effect of heterocycle unit on sensing performance". . . Retrieved 2020.
• 3、 Guo, Ailing,Zhu, Ruitao,Ren, Yuehong,Dong, Jinlong,Feng, Liheng. "A "turn-on" fluorescent chemosensor for aluminum ion and cell imaging application". . p. 530 - 534. Retrieved 2016.
• 4、 Chafaa, Salah,Chafai, Nadjib,Djenane, Meriem,Ghedjati, Samira,Houas, Noudjoud,Kitouni, Siham. "Synthesis, characterization, DFT study and antioxidant activity of (2-hydroxynaphthalen-1-yl) methyl 2-hydroxyphenyl amino phosphonic acid". . . Retrieved 2022.
• 5、 Sarma, Smita,Bhowmik, Ananya,Sarma, Manas Jyoti,Banu, Sofia,Phukan, Prodeep,Das, Diganta Kumar. "Condensation product of 2-hydroxy-1-napthaldehyde and 2-aminophenol: Selective fluorescent sensor for Al3+ ion and fabrication of paper strip sensor for Al3+ ion". . p. 202 - 208. Retrieved 2018.
• 6、 Jia, Wei-Guo,Wang, Zhi-Bao,Zhi, Xue-Ting. "Half-sandwich ruthenium complexes with Schiff base ligands bearing a hydroxyl group: Preparation, characterization and catalytic activities". . . Retrieved 2019/11/20.