2-STYRYLBENZENOL

Base Information

• Chemical Name: 2-STYRYLBENZENOL
• CAS No.: 18493-15-7
• Molecular Formula: C14H12O
• Molecular Weight: 196.249
• Hs Code.: 2907199090
• Mol file: 18493-15-7.mol

Synonyms:2-Stilbenol,(E)- (8CI);Phenol, 2-(2-phenylethenyl)-, (E)-;(E)-2-(2-Phenylethenyl)phenol;(E)-2-Hydroxystilbene;(E)-2-Stilbenol;2-Hydroxy-trans-stilbene;o-Hydroxy-(E)-stilbene;trans-2-Hydroxystilbene;

Chemical Property of 2-STYRYLBENZENOL

Chemical Property:

• Vapor Pressure: 5.22E-05mmHg at 25°C
• Melting Point: 144-146°C
• Refractive Index: 1.691
• Boiling Point: 337.8 °C at 760 mmHg
• Flash Point: 161.9 °C
• PSA: 20.23000
• Density: 1.147g/cm³
• LogP: 3.56260

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-STYRYLBENZENOL

There total 83 articles about 2-STYRYLBENZENOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + 2-Iodophenol (533-58-4) → (E)-2-hydroxystilbene (18493-15-7)

Guidance literature:

With bis(1,1'-ethylene-3,3'-divinylimidazole-2,2'-diylidene)nickel(II) dibromide dihydrate; potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 4h; Inert atmosphere; Schlenk technique;

DOI:10.1016/j.poly.2018.10.028

Reference yield: 97.0%

2-Allyloxystilbene → 2-[(E/Z)-2-phenylvinyl]phenol (18493-15-7,42224-48-6,3839-69-8)

Guidance literature:

With palladium diacetate; sodium hydride; In N,N-dimethyl acetamide; mineral oil; at 25 ℃; for 4h; Inert atmosphere;

Reference yield: 95.0%

1-benzofurane (271-89-6) + phenylmagnesium bromide (100-58-3) → (E)-2-hydroxystilbene (18493-15-7)

Guidance literature:

1-benzofurane; With bis(1,5-cyclooctadiene)nickel⁽⁰⁾; C₂₇H₃₉N₂⁽¹⁺⁾*Cl^(1-)*ClH; lithium chloride; In tetrahydrofuran; at -30 ℃; for 0.0333333h; Inert atmosphere;

phenylmagnesium bromide; In tetrahydrofuran; at 80 ℃; for 16h; stereoselective reaction; Inert atmosphere;

DOI:10.1021/ol4031815

upstream raw materials:

1-benzofurane

phenyllithium

α-benzyl-2-hydroxybenzylalcohol

(E)-2-methoxystilbene

Downstream raw materials:

(E)-2-stilbenyloxoacetic acid ethyl ester

2-(2-hydroxyphenyl)-1-phenylethan-1-one

2-phenylbenzofuran

2-hydroxystilbene sodium salt