1-Boc-4-phenylethynyl-piperidine

Base Information

Chemical Name:1-Boc-4-phenylethynyl-piperidine
CAS No.:669015-08-1
Molecular Formula:C18H23NO2
Molecular Weight:285.386
Hs Code.:2933399090
Mol file:669015-08-1.mol

Synonyms:1-Boc-4-Phenylethynyl-piperidine;4-phenylethynyl-piperidine-1-carboxylic acid tert-butyl ester;

Suppliers and Price of 1-Boc-4-phenylethynyl-piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-Boc-4-phenylethynyl-piperidine

Chemical Property:

Vapor Pressure:1.27E-06mmHg at 25°C
Boiling Point:400.5oC at 760 mmHg
PKA:-2.32±0.40(Predicted)
Flash Point:196oC
PSA：29.54000
Density:1.08g/cm3
LogP:3.62310

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-Boc-4-phenylethynyl-piperidine

There total 13 articles about 1-Boc-4-phenylethynyl-piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: diethyl 4-(1-(tert-butoxycarbonyl)piperidin-4-yl)-2,6-dimethyl-1,4 -dihydropyridine-3,5-dicarboxylate

: 1-Phenylethynyl-1H-1λ³-benzo[d][1,2]iodoxol-3-one

: 669015-08-1
tert-butyl 4-(phenylethynyl)piperidine-1-carboxylate

Guidance literature:: With tris[2-phenylpyridinato-C₂,N]iridium(III); In acetonitrile; at 20 ℃; for 24h; Irradiation; Inert atmosphere;
DOI:10.1016/j.tetlet.2019.151230

Reference yield: 73.5%

: 591-50-4
iodobenzene

: 287192-97-6
4-ethynyl-piperidine-1-carboxylic acid tert-butyl ester

: 669015-08-1
tert-butyl 4-(phenylethynyl)piperidine-1-carboxylate

Guidance literature:: With triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; at 82 ℃; for 17h;

Reference yield: 58.0%

: 1-(1-(tert-butoxycarbonyl)piperidin-4-yl)-2,4,6-triphenylpyridin-1-ium tetrafluoroborate

: 28995-88-2
1-methyl-4-((phenylethynyl)sulfonyl)benzene

: 669015-08-1
tert-butyl 4-(phenylethynyl)piperidine-1-carboxylate

Guidance literature:: With Eosin Y; N-ethyl-N,N-diisopropylamine; In methanol; 1,2-dichloro-ethane; at 20 - 22 ℃; for 16h; chemoselective reaction; Irradiation; Inert atmosphere;
DOI:10.1021/acscatal.8b03437