1-Octadecanoyl-2-acetyl-sn-glycero-3-phosphocholine

Base Information

Chemical Name:1-Octadecanoyl-2-acetyl-sn-glycero-3-phosphocholine
CAS No.:79549-26-1
Molecular Formula:C₂₈H₅₆NO₈P
Molecular Weight:565.728
Hs Code.:
DSSTox Substance ID:DTXSID601000586
Wikidata:Q27145170
Metabolomics Workbench ID:13481
Mol file:79549-26-1.mol

Synonyms:1-octadecanoyl-2-acetyl-sn-glycero-3-phosphocholine;79549-26-1;Platelet-activating factor C18;PC(18:0/2:0);1-stearoyl-2-acetyl-sn-glycero-3-phosphocholine;1-Stearoyl-2-acetyl-sn-glycero-3-phosphorylcholine;[(2R)-2-acetyloxy-3-octadecanoyloxypropyl] 2-(trimethylazaniumyl)ethyl phosphate;CHEBI:75220;DTXSID601000586;LMGP01010779;1-octadecanoyl-2-acetyl-sn-phosphatidylcholine;Q27145170;(2R)-2-acetoxy-3-(stearoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate;(2R)-2-acetoxy-3-(octadecanoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate;2-(Acetyloxy)-3-(octadecanoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate;3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-, hydroxide, inner salt, 4-oxide, (R)-;3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-, inner salt, 4-oxide, (R)-;7-(Acetyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacosan-1-aminium hydroxide, inner salt, 4-oxide, (R)-

Suppliers and Price of 1-Octadecanoyl-2-acetyl-sn-glycero-3-phosphocholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-Octadecanoyl-2-acetyl-sn-glycero-3-phosphocholine

Chemical Property:

PSA：121.00000
LogP:7.00080
Storage Temp.:−20°C
Solubility.:chloroform: 10 mg/mL
XLogP3:7.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:28
Exact Mass:565.37435474
Heavy Atom Count:38
Complexity:645

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)C
Isomeric SMILES:CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)C

Technology Process of 1-Octadecanoyl-2-acetyl-sn-glycero-3-phosphocholine

There total 7 articles about 1-Octadecanoyl-2-acetyl-sn-glycero-3-phosphocholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.5%

: Cholin-p-toluolsulfonsaeureester

: 83542-44-3
2-O-Acetyl-1-O-octadecanoyl-sn-glycerin

: 79549-26-1
2-O-Acetyl-1-O-octadecanoyl-sn-glyceryl-3-phosphorylcholin

Guidance literature:: With pyridine; triethylamine; trichlorophosphate; In chloroform; Ambient temperature;
DOI:10.1002/hlca.19820650339

Reference yield: 58.0%

: 1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine

: 108-24-7
acetic anhydride

: 79549-26-1
2-O-Acetyl-1-O-octadecanoyl-sn-glyceryl-3-phosphorylcholin

Guidance literature:: With dmap; In dichloromethane; at 20 ℃; for 30h; Inert atmosphere;

Reference yield:

: 4145-51-1,6236-22-2,116947-35-4,988-76-1
3-O-Benzyl-1-O-octadecanoyl-sn-glycerin

: 79549-26-1
2-O-Acetyl-1-O-octadecanoyl-sn-glyceryl-3-phosphorylcholin

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / CHCl₃ / Ambient temperature

2: H₂ / 5percent Pd/C / tetrahydrofuran / Ambient temperature

3: 60.5 percent / phosphorus oxychloride, Et₃N, pyridine / CHCl₃ / Ambient temperature

With pyridine; hydrogen; triethylamine; trichlorophosphate; palladium on activated charcoal; In tetrahydrofuran; chloroform;
DOI:10.1002/hlca.19820650339