2-amino-N-cyclopropylacetamide hydrochloride

Base Information

• Chemical Name: 2-amino-N-cyclopropylacetamide hydrochloride
• CAS No.: 670253-51-7
• Molecular Formula: C5H10N2O.ClH
• Molecular Weight: 150.60700
• Hs Code.: 2924299090
• European Community (EC) Number: 800-599-6
• DSSTox Substance ID: DTXSID80585825
• Mol file: 670253-51-7.mol

Synonyms:2-amino-N-cyclopropylacetamide hydrochloride;670253-51-7;2-Amino-n-cyclopropylacetamide, HCl;MFCD07323617;2-AMINO-N-CYCLOPROPYLACETAMIDE HCL;2-amino-N-cyclopropylacetamide;hydrochloride;N1-Cyclopropylglycinamide hydrochloride;SCHEMBL1996186;DTXSID80585825;2-Amino-n-cyclopropylacetamide,HCl;VBB25351;AB1061;AKOS015949021;AS-44500;SY239805;CS-0077363;EN300-13919;N-Cyclopropylglycinamide--hydrogen chloride (1/1);N1-Cyclopropylglycinamide hydrochloride, AldrichCPR;Acetamide, 2-amino-N-cyclopropyl-, monohydrochloride;Z94599161

Chemical Property of 2-amino-N-cyclopropylacetamide hydrochloride

Chemical Property:

• PSA: 58.61000
• LogP: 1.56630
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 150.0559907
• Heavy Atom Count: 9
• Complexity: 98.6

Purity/Quality:

97% ^*data from raw suppliers

2-Amino-n-cyclopropylacetamidehydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC1NC(=O)CN.Cl
• Uses: 2-Amino-n-cyclopropylacetamide, HCl

Technology Process of 2-amino-N-cyclopropylacetamide hydrochloride

There total 2 articles about 2-amino-N-cyclopropylacetamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl 2-(cyclopropylamino)-2-oxoethylcarbamate (1228594-39-5) → 2-amino-N-cyclopropylacetamide hydrochloride (670253-51-7)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; water; for 2h;

Reference yield:

→ 2-amino-N-cyclopropylacetamide hydrochloride (670253-51-7)

Guidance literature:

Reference yield: 73.0%

2-ethynyl-thiophene (4298-52-6) + 2-amino-N-cyclopropylacetamide hydrochloride (670253-51-7) → N-cyclopropyl-5-(thiophen-2-yl)isoxazole-3-carboxamide (832115-62-5)

Guidance literature:

With tert.-butylnitrite; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; sodium hydrogencarbonate; zinc dibromide; In tert-butyl methyl ether; at 20 ℃; for 24h; Schlenk technique; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.joc.0c02281

upstream raw materials:

tert-butyl 2-(cyclopropylamino)-2-oxoethylcarbamate

Downstream raw materials:

N-cyclopropyl-5-(thiophen-2-yl)isoxazole-3-carboxamide