Propanedioic acid, [(2-chlorophenyl)methyl]-, dimethyl ester

Base Information

Chemical Name:Propanedioic acid, [(2-chlorophenyl)methyl]-, dimethyl ester
CAS No.:670748-78-4
Molecular Formula:C12H13ClO4
Molecular Weight:256.686
Hs Code.:
DSSTox Substance ID:DTXSID00478023
Wikidata:Q82311173

Synonyms:670748-78-4;Propanedioic acid, [(2-chlorophenyl)methyl]-, dimethyl ester;SCHEMBL9767979;DTXSID00478023

Suppliers and Price of Propanedioic acid, [(2-chlorophenyl)methyl]-, dimethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Propanedioic acid, [(2-chlorophenyl)methyl]-, dimethyl ester

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:256.0502366
Heavy Atom Count:17
Complexity:264

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C(CC1=CC=CC=C1Cl)C(=O)OC

Technology Process of Propanedioic acid, [(2-chlorophenyl)methyl]-, dimethyl ester

There total 5 articles about Propanedioic acid, [(2-chlorophenyl)methyl]-, dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 17849-38-6
2-Chlorobenzyl alcohol

: 18424-76-5
sodiodimethylmalonate

: 670748-78-4
dimethyl 2-(2-chlorobenzyl)malonate

Guidance literature:: 2-Chlorobenzyl alcohol; With trifluoromethylsulfonic anhydride; 1,1'-sulfinylbisbenzene; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; In toluene; at -78 ℃;

sodiodimethylmalonate; In tetrahydrofuran; toluene; at -78 - 20 ℃;
DOI:10.1246/cl.2004.8

Reference yield: 74.0%

: 611-17-6
1-bromomethyl-2-chlorobenzene

: 108-59-8
malonic acid dimethyl ester

: 670748-78-4
dimethyl 2-(2-chlorobenzyl)malonate

Guidance literature:: malonic acid dimethyl ester; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 0.5h;

1-bromomethyl-2-chlorobenzene; In tetrahydrofuran; at 20 ℃;
DOI:10.1002/anie.202014605