Methyl 2-fluoro-3-hydroxypropanoate

Base Information

Chemical Name:Methyl 2-fluoro-3-hydroxypropanoate
CAS No.:671-30-7
Molecular Formula:C4H7FO3
Molecular Weight:122.096
Hs Code.:2918199890
European Community (EC) Number:614-020-8
DSSTox Substance ID:DTXSID80697093
Mol file:671-30-7.mol

Synonyms:Methyl 2-fluoro-3-hydroxypropanoate;671-30-7;2-FLUORO-3-HYDROXYPROPANOIC ACID METHYL ESTER;SCHEMBL13583797;DTXSID80697093;Methyl2-fluoro-3-hydroxypropanoate;AMY36965;Methyl 2-fluoro-3-hydroxypropionate;MFCD16622008;SB84339;AS-33347;CS-0027052;A867329

Suppliers and Price of Methyl 2-fluoro-3-hydroxypropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl2-Fluoro-3-hydroxypropanoate
25mg
$ 70.00

TRC
Methyl2-Fluoro-3-hydroxypropanoate
10mg
$ 55.00

Crysdot
Methyl2-fluoro-3-hydroxypropanoate 97%
1g
$ 395.00

Crysdot
Methyl2-fluoro-3-hydroxypropanoate 97%
250mg
$ 235.00

American Custom Chemicals Corporation
METHYL-2-FLUORO-3-HYDROXYPROPANOATE 95.00%
5MG
$ 505.64

AK Scientific
Methyl2-fluoro-3-hydroxypropanoate
25g
$ 2451.00

Total 31 raw suppliers

Chemical Property of Methyl 2-fluoro-3-hydroxypropanoate

Chemical Property:

Vapor Pressure:0.0996mmHg at 25°C
Boiling Point:196.9oC at 760 mmHg
PKA:13.31±0.10(Predicted)
Flash Point:72.9oC
PSA：46.53000
Density:1.204g/cm3
LogP:-0.51020
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:-0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:122.03792224
Heavy Atom Count:8
Complexity:83.4

Purity/Quality:

97% ^*data from raw suppliers

Methyl2-Fluoro-3-hydroxypropanoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C(CO)F
Uses Methyl 2-Fluoro-3-hydroxypropanoate is used in preparation of cyclopeptide containing heteroaryl compounds for treatment of cancers.

Technology Process of Methyl 2-fluoro-3-hydroxypropanoate

There total 2 articles about Methyl 2-fluoro-3-hydroxypropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67-56-1
methanol

: 2368-38-9
2-fluoro-3-hydroxy-propionaldehyde

: 671-30-7
methyl 3-hydroxy-2-fluoropropionate

Guidance literature:: Multistep reaction; (i) I₂, BaI₂, aq. Ba(OH)2, (ii) /BRN= 1098229/, H₂SO₄;
DOI:10.1039/jr9600000106

Reference yield:

: 671-30-7
methyl 3-hydroxy-2-fluoropropionate

Guidance literature:: (+-)-2-Fluor-2-desoxy-glycinaldehyd 1) Hypoiodit-Lsg. <-> Saeure (als Bleisalz isoliert)> 2) methanol. H2SO4, 7h, Kochen;
DOI:10.1039/jr9600000106