ethyl 3-(2,3-dichlorophenyl)-3-oxopropanoate

Base Information

• Chemical Name: ethyl 3-(2,3-dichlorophenyl)-3-oxopropanoate
• CAS No.: 672323-07-8
• Molecular Formula: C11H10Cl2O3
• Molecular Weight: 261.105
• Mol file: 672323-07-8.mol

Synonyms:

Chemical Property of ethyl 3-(2,3-dichlorophenyl)-3-oxopropanoate

Chemical Property:

• PSA: 43.37000
• LogP: 3.12930

Purity/Quality:

99% ^*data from raw suppliers

ETHYL-3-(2,3-DICHLOROPHENYL)-3-OXOPROPANOATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ethyl 3-(2,3-dichlorophenyl)-3-oxopropanoate

There total 2 articles about ethyl 3-(2,3-dichlorophenyl)-3-oxopropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

→ ethyl 3-(2,3-dichlorophenyl)-3-oxopropanoate (672323-07-8)

Guidance literature:

Reference yield:

2,3-dichlorobenzoyl chloride (2905-60-4) + ethyl acetate (141-78-6) → ethyl 3-(2,3-dichlorophenyl)-3-oxopropanoate (672323-07-8)

Guidance literature:

ethyl acetate; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

2,3-dichlorobenzoyl chloride; In tetrahydrofuran; hexane; at -70 - -65 ℃; for 0.5h;

Reference yield: 33.4%

ethyl 3-(2,3-dichlorophenyl)-3-oxopropanoate (672323-07-8) + methylhydrazine sulfuric acid (302-15-8) → 3-(2,3-dichlorophenyl)-1-methyl-1H-pyrazol-5-ol

Guidance literature:

With triethylamine; In ethanol; at 25 - 80 ℃; for 2h;

upstream raw materials:

2,3-dichlorobenzoyl chloride

ethyl acetate

Refernces

• 1、 -. "PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS". Page/Page column 32. . Retrieved 2008/06/13.
• 2、 -. "PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS". Page 33. . Retrieved 2008/06/13.