Technology Process of Piperovatine
There total 19 articles about Piperovatine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: CuI / (Ph3P)2PdCl2 / triethylamine
2: 1.) H2; 2.) NEt3 / 1.) Pd/C / 1.) EtOAc; 2.) DMSO, CH2Cl2
3: piperidine / acetonitrile
4: DMAP / pyridine
5: 73 percent / bis-trimethylsilylacetamide / Mo(CO)6 / toluene
6: 1.) aq. HCl; 2.) phenyl N-phenylphosphoramidochloridate, NEt3 / 1.) dioxane; 2.) CH2Cl2
With
piperidine; hydrogenchloride; dmap; copper(l) iodide; N,O-bis-(trimethylsilyl)-acetamide; hydrogen; triethylamine; Phenyl N-phenylphosphoramidochloridate;
bis-triphenylphosphine-palladium(II) chloride; palladium on activated charcoal; hexacarbonyl molybdenum;
In
pyridine; triethylamine; toluene; acetonitrile;
DOI:10.1016/S0040-4039(00)84756-5
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) H2; 2.) NEt3 / 1.) Pd/C / 1.) EtOAc; 2.) DMSO, CH2Cl2
2: piperidine / acetonitrile
3: DMAP / pyridine
4: 73 percent / bis-trimethylsilylacetamide / Mo(CO)6 / toluene
5: 1.) aq. HCl; 2.) phenyl N-phenylphosphoramidochloridate, NEt3 / 1.) dioxane; 2.) CH2Cl2
With
piperidine; hydrogenchloride; dmap; N,O-bis-(trimethylsilyl)-acetamide; hydrogen; triethylamine; Phenyl N-phenylphosphoramidochloridate;
palladium on activated charcoal; hexacarbonyl molybdenum;
In
pyridine; toluene; acetonitrile;
DOI:10.1016/S0040-4039(00)84756-5
- Guidance literature:
-
Multi-step reaction with 4 steps
1: piperidine / acetonitrile
2: DMAP / pyridine
3: 73 percent / bis-trimethylsilylacetamide / Mo(CO)6 / toluene
4: 1.) aq. HCl; 2.) phenyl N-phenylphosphoramidochloridate, NEt3 / 1.) dioxane; 2.) CH2Cl2
With
piperidine; hydrogenchloride; dmap; N,O-bis-(trimethylsilyl)-acetamide; triethylamine; Phenyl N-phenylphosphoramidochloridate;
hexacarbonyl molybdenum;
In
pyridine; toluene; acetonitrile;
DOI:10.1016/S0040-4039(00)84756-5
