1-(P-Chlorobenzoyl)-5-methoxy-2-methylindole

Base Information

Chemical Name:1-(P-Chlorobenzoyl)-5-methoxy-2-methylindole
CAS No.:6260-97-5
Molecular Formula:C17H14ClNO2
Molecular Weight:299.757
Hs Code.:
UNII:W075O86E5T
DSSTox Substance ID:DTXSID20211656
Nikkaji Number:J1.566.963B
Wikidata:Q27292129
ChEMBL ID:CHEMBL2323483

Synonyms:6260-97-5;(4-chlorophenyl)(5-methoxy-2-methyl-1H-indol-1-yl)methanone;1-(P-CHLOROBENZOYL)-5-METHOXY-2-METHYLINDOLE;UNII-W075O86E5T;CHEMBL2323483;HSDB 6011;W075O86E5T;Indole, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-;1H-Indole, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-;Indole,1-(p-chlorobenzoyl)-5-methoxy-2-methyl-;1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole;SCHEMBL11037919;(4-chlorophenyl)-(5-methoxy-2-methylindol-1-yl)methanone;DTXSID20211656;BDBM50427654;FT-0715232;Q27292129;1-(P-CHLOROBENZOYL)-5-METHOXY-2-METHYLINDOLE [HSDB];METHANONE, (4-CHLOROPHENYL)(5-METHOXY-2-METHYL-1H-INDOL-1-YL)-

Suppliers and Price of 1-(P-Chlorobenzoyl)-5-methoxy-2-methylindole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 1-(P-Chlorobenzoyl)-5-methoxy-2-methylindole

Chemical Property:

Vapor Pressure:1.91E-06mmHg at 25°C
Boiling Point:394.9°Cat760mmHg
Flash Point:192.6°C
Density:1.23g/cm³
XLogP3:4.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:299.0713064
Heavy Atom Count:21
Complexity:381

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Nitrogen Compounds -> Indoles
Canonical SMILES:CC1=CC2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC

Technology Process of 1-(P-Chlorobenzoyl)-5-methoxy-2-methylindole

There total 9 articles about 1-(P-Chlorobenzoyl)-5-methoxy-2-methylindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 4-chloro-N-(4-methoxy-2-(prop-1-en-2-yl)phenyl)benzamide

: 6260-97-5
(4-chlorophenyl)(5-methoxy-2-methyl-1H-indol-1-yl)methanone

Guidance literature:: With (phenyliodonio)sulfamate; water; In acetonitrile; at 60 ℃; regioselective reaction;
DOI:10.1021/acs.orglett.8b01615

Reference yield: 71.0%

: C₁₇H₁₆ClNO₂

: 6260-97-5
(4-chlorophenyl)(5-methoxy-2-methyl-1H-indol-1-yl)methanone

Guidance literature:: With palladium diacetate; dibutyl phosphate; p-benzoquinone; In dimethyl sulfoxide; at 60 - 70 ℃; Inert atmosphere;
DOI:10.3390/molecules25051233

Reference yield: 25.0%

: 1076-74-0
5-methoxy-2-methyl-1H-indole

: 122-01-0
4-chloro-benzoyl chloride

: 68327-44-6
(5-methoxy-2-methyl-1H-indole-1,3-diyl)bis((4-chlorophenyl)methanone)

: 6260-97-5
(4-chlorophenyl)(5-methoxy-2-methyl-1H-indol-1-yl)methanone

Guidance literature:: 5-methoxy-2-methyl-1H-indole; With sodium t-butanolate; In tetrahydrofuran; at 0 - 5 ℃; for 0.416667h;

4-chloro-benzoyl chloride; In tetrahydrofuran; at 20 ℃;
DOI:10.1016/j.tet.2012.08.044 DOI:10.1016/j.tet.2012.08.044