4-(Diethylamino)-1-phenyl-1-(2-thienyl)-2-butyn-1-ol

Base Information

Chemical Name:4-(Diethylamino)-1-phenyl-1-(2-thienyl)-2-butyn-1-ol
CAS No.:1156-12-3
Molecular Formula:C₁₈H₂₁NOS
Molecular Weight:299.437
Hs Code.:
DSSTox Substance ID:DTXSID50921771
Nikkaji Number:J77.538J

Synonyms:1156-12-3;BRN 3977854;4-(Diethylamino)-1-phenyl-1-(2-thienyl)-2-butyn-1-ol;DTXSID50921771;2-Butyn-1-ol, 4-(diethylamino)-1-phenyl-1-(2-thienyl)-;EU-0046200;4-(diethylamino)-1-phenyl-1-(thiophen-2-yl)but-2-yn-1-ol

Suppliers and Price of 4-(Diethylamino)-1-phenyl-1-(2-thienyl)-2-butyn-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 0 raw suppliers

Chemical Property of 4-(Diethylamino)-1-phenyl-1-(2-thienyl)-2-butyn-1-ol

Chemical Property:

Vapor Pressure:2.93E-09mmHg at 25°C
Boiling Point:460.1°Cat760mmHg
Flash Point:232°C
Density:1.139g/cm³
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:299.13438547
Heavy Atom Count:21
Complexity:375

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)CC#CC(C1=CC=CC=C1)(C2=CC=CS2)O

Technology Process of 4-(Diethylamino)-1-phenyl-1-(2-thienyl)-2-butyn-1-ol

There total 3 articles about 4-(Diethylamino)-1-phenyl-1-(2-thienyl)-2-butyn-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 71228-44-9
1-phenyl-1-(thiophene-2-yl)-prop-2-yn-1-ol

: 109-89-7
diethylamine

: 1156-12-3
(+/-)-4-Diethylamino-1-phenyl-1-(2-thienyl)-but-2-in-1-ol

Guidance literature:: With copper(l) chloride;
DOI:10.1007/BF00772992

Reference yield:

: 135-00-2
2-Benzoylthiophene

: 1156-12-3
(+/-)-4-Diethylamino-1-phenyl-1-(2-thienyl)-but-2-in-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / liquid ammonia

2: 49 percent / CuCl

With copper(l) chloride; In ammonia;
DOI:10.1007/BF00772992