1-[2-(4-Nitrophenoxy)ethyl]pyrrolidine--hydrogen chloride (1/1)

Base Information

Chemical Name:1-[2-(4-Nitrophenoxy)ethyl]pyrrolidine--hydrogen chloride (1/1)
CAS No.:85002-96-6
Molecular Formula:C12H16N2O3
Molecular Weight:272.732
Hs Code.:
DSSTox Substance ID:DTXSID00510977
NSC Number:118952

Synonyms:85002-96-6;DTXSID00510977;NSC118952;NSC-118952;1-[2-(4-Nitrophenoxy)ethyl]pyrrolidine--hydrogen chloride (1/1)

Suppliers and Price of 1-[2-(4-Nitrophenoxy)ethyl]pyrrolidine--hydrogen chloride (1/1)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-[2-(4-Nitrophenoxy)ethyl]pyrrolidine--hydrogen chloride (1/1)

Chemical Property:

Vapor Pressure:5.93E-06mmHg at 25°C
Refractive Index:1.562
Boiling Point:379.3°Cat760mmHg
Flash Point:183.2°C
Density:1.195g/cm³
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:272.0927701
Heavy Atom Count:18
Complexity:241

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C1)CCOC2=CC=C(C=C2)[N+](=O)[O-].Cl

Technology Process of 1-[2-(4-Nitrophenoxy)ethyl]pyrrolidine--hydrogen chloride (1/1)

There total 2 articles about 1-[2-(4-Nitrophenoxy)ethyl]pyrrolidine--hydrogen chloride (1/1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 1124-31-8
potassium 4-nitrophenolate

: 7250-67-1
1-(2-chloroethyl)pyrrolidine hydrochloride

: 85002-96-6
1-(2-(4-nitrophenoxy)ethyl)pyrrolidine hydrochloride

Guidance literature:: 1-(2-chloroethyl)pyrrolidine hydrochloride; With potassium hydroxide; In water;

potassium 4-nitrophenolate; In toluene; Reflux;

With hydrogenchloride; In ethyl acetate; at 0 ℃;
DOI:10.1016/j.bmc.2010.11.005

Reference yield: 53.3%

: 2955-88-6
1-pyrrolidineethanol

: 100-00-5
4-chlorobenzonitrile

: 85002-96-6
1-(2-(4-nitrophenoxy)ethyl)pyrrolidine hydrochloride

Guidance literature:: With sodium hydride; In dimethyl sulfoxide; at 70 ℃; for 0.5h;
DOI:10.1248/cpb.30.3580

Reference yield: 94.0%

: 85002-96-6
1-(2-(4-nitrophenoxy)ethyl)pyrrolidine hydrochloride

: 4-(2-(pyrrolidin-1-yl)ethoxy)benzenamine hydrochloride

Guidance literature:: With 10% palladium on activated carbon; hydrogen; In ethyl acetate; for 2h; under 1810.07 Torr;
DOI:10.1016/j.bmc.2010.11.005