(1-Ethoxyethyl)benzene

Base Information

• Chemical Name: (1-Ethoxyethyl)benzene
• CAS No.: 3299-05-6
• Molecular Formula: C10H14 O
• Molecular Weight: 150.221
• Hs Code.: 2909309090
• European Community (EC) Number: 221-968-2
• NSC Number: 104
• UNII: 2E2F35SUC3
• DSSTox Substance ID: DTXSID201347798
• Nikkaji Number: J47.446K
• Mol file: 3299-05-6.mol

Synonyms:(1-ETHOXYETHYL)BENZENE;1-ethoxyethylbenzene;3299-05-6;Benzene, (1-ethoxyethyl)-;.alpha.-Methylbenzyl ethyl ether;(1-Ethoxy-ethyl)-benzene;.alpha.-Phenyldiethyl ether;2E2F35SUC3;NSC-104;Ether, ethyl .alpha.-methylbenzyl;Benzene, ethoxyethyl-;Phenylather;alpha-Phenyldiethyl ether;1-Ethoxy-1-phenylethane;1-Phenylethyl ethyl ether;(1-Ethoxyethyl)benzene #;UNII-2E2F35SUC3;alpha-Methylbenzyl ethyl ether;SCHEMBL585596;NSC104;SCHEMBL7644979;ETHYL 1-PHENYLETHYL ETHER;NSC 104;DTXSID201347798;EINECS 221-968-2

Chemical Property of (1-Ethoxyethyl)benzene

Chemical Property:

• Vapor Pressure: 1.07mmHg at 25°C
• Boiling Point: 183.1°Cat760mmHg
• Flash Point: 60.2°C
• PSA: 9.23000
• Density: 0.925g/cm³
• LogP: 2.78410
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 150.104465066
• Heavy Atom Count: 11
• Complexity: 95

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(C)C1=CC=CC=C1
• General Description: (1-Ethoxyethyl)benzene, also known as 1-ethoxy-1-phenylethane or α-methylbenzyl ethyl ether, is a chemical compound characterized by an ethoxy group attached to a phenylethyl framework. It is classified as an ether derivative and is used in organic synthesis, particularly as a protecting group for alcohols or as an intermediate in the preparation of other functionalized aromatic compounds. (1-ethoxyethyl)benzene exhibits typical ether-like properties, including moderate volatility and solubility in organic solvents. Its structure allows for reactivity at the benzylic position, making it useful in various chemical transformations. No further specific data on its physical or chemical properties are provided in the given context.

Technology Process of (1-Ethoxyethyl)benzene

There total 64 articles about (1-Ethoxyethyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.7%

1,1,-diethoxy-1-phenylethane (4316-37-4) → 1-ethoxy-1-phenylethane (3299-05-6)

Guidance literature:

With triethylsilane; Nafion-H (perfluororesinsulfonic acid); In dichloromethane; for 2h; Heating;

DOI:10.1021/jo00364a044

Reference yield: 90.0%

ethanol (64-17-5) + 1-Phenylethanol (98-85-1,13323-81-4) → 1-ethoxy-1-phenylethane (3299-05-6)

Guidance literature:

With zinc(II) chloride; In 1,2-dichloro-ethane; at 80 ℃; for 2h;

DOI:10.1021/jo00226a036

Reference yield: 89.0%

diethyl acetal (105-57-7,30846-29-8) → 1-ethoxy-1-phenylethane (3299-05-6)

Guidance literature:

In diethyl ether; at -30 ℃; for 0.5h;

DOI:10.1016/0040-4039(84)80011-8

upstream raw materials:

styrene

ethanol

diethyl acetal

1-Phenylethanol

Downstream raw materials:

styrene

1-phenylethyl hydroperoxide

ethanol

acetophenone