N-Phenyl-N-thienylacetamide

Base Information

• Chemical Name: N-Phenyl-N-thienylacetamide
• CAS No.: 19320-17-3
• Molecular Formula: C12H11NOS
• Molecular Weight: 217.2868
• DSSTox Substance ID: DTXSID80940995
• Wikidata: Q82917760
• Mol file: 19320-17-3.mol

Synonyms:N-2-Thienylacetanilide;N-Phenyl-N-thienylacetamide;BRN 0156928;ACETANILIDE, N-2-THIENYL-;19320-17-3;4-18-00-07063 (Beilstein Handbook Reference);N-(2-thienyl)acetanilide;SCHEMBL7982643;DTXSID80940995;NSWHPDKDCAZMJE-UHFFFAOYSA-N;AKOS000280001;N-PHENYL-N-(THIOPHEN-2-YL)ACETAMIDE

Chemical Property of N-Phenyl-N-thienylacetamide

Chemical Property:

• Vapor Pressure: 1.88E-07mmHg at 25°C
• Boiling Point: 425.6°Cat760mmHg
• Flash Point: 211.2°C
• Density: 1.226g/cm³
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 217.05613515
• Heavy Atom Count: 15
• Complexity: 226

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(=O)N(C1=CC=CC=C1)C2=CC=CS2

Technology Process of N-Phenyl-N-thienylacetamide

There total 2 articles about N-Phenyl-N-thienylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Iodothiophene (3437-95-4,149762-92-5) + copper(I) iodide (7681-65-4) + Acetanilid (103-84-4) → N-phenyl-N-[2]thienyl-acetamide (19320-17-3)

Guidance literature:

With potassium carbonate; In water; ethyl acetate;

Reference yield:

2-bromothiophene (1003-09-4) → N-phenyl-N-[2]thienyl-acetamide (19320-17-3)

Guidance literature:

With potassium carbonate; Acetanilid; at 170 ℃; kleine Mengen Kaliumjodid, Kupfer-Pulver und Jod in Nitrobenzol;

DOI:10.1021/ja01123a071

upstream raw materials:

2-bromothiophene

2-Iodothiophene

copper(I) iodide

Acetanilid