3-Acetylpyridine oxime

Base Information

• Chemical Name: 3-Acetylpyridine oxime
• CAS No.: 5973-83-1
• Molecular Formula: C7H8N2O
• Molecular Weight: 136.153
• European Community (EC) Number: 611-872-2
• NSC Number: 72375
• Mol file: 5973-83-1.mol

Synonyms:3-Acetylpyridine oxime;5973-83-1;106881-77-0;1-(3-pyridinyl)-1-ethanone oxime;Ethanone, 1-(3-pyridinyl)-, oxime;(E)-1-(pyridin-3-yl)ethanone oxime;KETONE, METHYL 3-PYRIDYL, OXIME;960622-18-8;1-(Pyridin-3-yl)ethanone oxime;NSC 72375;Methyl 3-pyridyl ketoxime;(NE)-N-(1-pyridin-3-ylethylidene)hydroxylamine;(Z)-1-(Pyridin-3-yl)ethanone oxime;BRN 0114168;Ethanone, 1-(3-pyridinyl)-, oxime, (1E)- (9CI);(E)-N-[1-(pyridin-3-yl)ethylidene]hydroxylamine;5-21-07-00395 (Beilstein Handbook Reference);1-Pyridin-3-yl-ethanone oxime;(1E)-N-hydroxy-1-(pyridin-3-yl)ethanimine;MFCD06245407;3-Acetylpyridineoxime;Ethanone, 1-(3-pyridinyl)-, oxime (9CI);Methyl-3-pyridyldetoxime;WLN: T6NJ CY1&UNQ;1-Pyridin-3-ylethanone oxime;(E)-din-3-yl)ethanone oxime;SCHEMBL3144867;MSRXORUOQNNOKN-RMKNXTFCSA-N;AMY24823;NSC72375;(E)-1-(pyridin-3-yl)ethanoneoxime;BBL036784;MFCD00179685;NSC-72375;STK594571;(1E)-1-(3-Pyridinyl)ethanone oxime;AKOS005072877;CS-W001846;HC-0709;(1E)-1-(3-Pyridinyl)ethanone oxime #;LS-87320;A8380;CS-0369386;EN300-101602;J-501998

Chemical Property of 3-Acetylpyridine oxime

Chemical Property:

• Vapor Pressure: 0.00222mmHg at 25°C
• Melting Point: 103 °C
• Refractive Index: 1.55
• Boiling Point: 277.1 °C at 760 mmHg
• Flash Point: 121.4 °C
• PSA: 45.48000
• Density: 1.11 g/cm³
• LogP: 1.27980
• Storage Temp.: Inert atmosphere,Room Temperature
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 136.063662883
• Heavy Atom Count: 10
• Complexity: 134

Purity/Quality:

99% ^*data from raw suppliers

1-Pyridin-3-yl-ethanoneOxime ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=NO)C1=CN=CC=C1
• Isomeric SMILES: C/C(=N\O)/C1=CN=CC=C1

Technology Process of 3-Acetylpyridine oxime

There total 2 articles about 3-Acetylpyridine oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methyl-3-pyridylketone (350-03-8) → 1-(pyridin-3-yl)ethan-1-one oxime (5973-83-1)

Guidance literature:

With hydroxylamine hydrochloride; In methanol; for 5h; Reflux;

DOI:10.1080/10286020.2018.1462341

Reference yield:

→ 1-(pyridin-3-yl)ethan-1-one oxime (5973-83-1)

Guidance literature:

With pyridine; hydroxylamine hydrochloride; In ethanol; for 4h; Reflux;

Reference yield: 97.0%

p-toluenesulfonyl chloride (98-59-9) + 1-(pyridin-3-yl)ethan-1-one oxime (5973-83-1) → 1-pyridin-3-yl-ethanone oxime O-tosylate (74209-51-1)

Guidance literature:

With pyridine; at 0 - 20 ℃; for 16h;

DOI:10.1080/10286020.2018.1462341

upstream raw materials:

methyl-3-pyridylketone

Downstream raw materials:

1-pyridin-3-yl-ethylamine

1-pyridin-3-yl-ethanone oxime O-tosylate

C₁₇H₁₆N₂

6-ethyl-3-methyl-5-phenyl-1,4-naphthyridine