4-(4-chlorobenzyl)phthalazin-1(2H)-one

Base Information Edit

Chemical Name:4-(4-chlorobenzyl)phthalazin-1(2H)-one
CAS No.:53242-88-9
Molecular Formula:C15H11ClN2O
Molecular Weight:270.718
Hs Code.:2933998350
European Community (EC) Number:258-445-3
UNII:56DW142LLX
DSSTox Substance ID:DTXSID50201343
Nikkaji Number:J295.913E
Wikidata:Q27261402
ChEMBL ID:CHEMBL63976
Mol file:53242-88-9.mol

Synonyms:53242-88-9;4-(4-chlorobenzyl)phthalazin-1(2H)-one;4-(4-Chloro-benzyl)-2H-phthalazin-1-one;4-[(4-chlorophenyl)methyl]-2H-phthalazin-1-one;4-(4-chlorobenzyl)phthalazin-1-ol;MLS000547504;4-(4-chlorobenzyl)-1(2H)-phthalazinone;4-[(4-Chlorophenyl)methyl]-1(2H)-phthalazinone;UNII-56DW142LLX;4-(4-Chlorobenzyl)-2H-phthalazin-1-one;CHEMBL63976;56DW142LLX;EINECS 258-445-3;4-[(4-CHLOROPHENYL)METHYL]PHTHALAZIN-1(2H)-ONE;SMR000113649;4-((4-Chlorophenyl)methyl)phthalazin-1(2H)-one;1(2H)-Phthalazinone, 4-((4-chlorophenyl)methyl)-;1(2H)-Phthalazinone, 4-[(4-chlorophenyl)methyl]-;4-{[4-chlorophenyl]methyl}-1(2H)-phthalazinone;4-((4-CHLOROPHENYL)METHYL)-1(2H)-PHTHALAZINONE;4-(4-Chlorobenzyl)-2H-phthalazin-1-one 1g;D0Q2SI;Oprea1_490645;cid_104452;SCHEMBL1789242;BDBM56339;DTXSID50201343;AZELASTINE IMPURITY D(USP);HMS2330L09;MFCD02168779;AKOS015918495;AC-4493;4(4-chlorobenzyl)-1(2H)-phthalazinone;NCGC00247234-01;AS-15947;CS-0156014;FT-0658923;4-(4-Chlorophenylmethyl)phthalazin-1(2H)-one;1(2H)-PHTHALAZINONE, 4-P-CHLOROBENZYL-;A829472;W-109042;Q27261402;AZELASTINE HYDROCHLORIDE IMPURITY D [EP IMPURITY]

Suppliers and Price of 4-(4-chlorobenzyl)phthalazin-1(2H)-one

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-[(4-Chlorophenyl)methyl]-1(2H)-phthalazinone
10g
$ 605.00

TRC
4-[(4-Chlorophenyl)methyl]-1(2H)-phthalazinone
2.5g
$ 175.00

Sigma-Aldrich
Azelastine impurity D
20mg
$ 1160.00

Sigma-Aldrich
Azelastine impurity D European Pharmacopoeia (EP) Reference Standard
y0000328
$ 190.00

Medical Isotopes, Inc.
4-[(4-Chlorophenyl)methyl]-1(2H)-phthalazinone
2.5 g
$ 640.00

Crysdot
4-(4-Chlorobenzyl)phthalazin-1(2H)-one 97%
25g
$ 1406.00

Crysdot
4-(4-Chlorobenzyl)phthalazin-1(2H)-one 97%
5g
$ 389.00

Crysdot
4-(4-Chlorobenzyl)phthalazin-1(2H)-one 97%
10g
$ 738.00

Chemenu
4-(4-Chlorobenzyl)phthalazin-1(2H)-one 95%
10g
$ 697.00

Chemenu
4-(4-Chlorobenzyl)phthalazin-1(2H)-one 95%
5g
$ 367.00

Total 44 raw suppliers

Chemical Property of 4-(4-chlorobenzyl)phthalazin-1(2H)-one Edit

Chemical Property:

Vapor Pressure:1.57E-11mmHg at 25°C
Melting Point:206-207 °C(Solv: ethanol (64-17-5))
Refractive Index:1.66
Boiling Point:522.3 °C at 760 mmHg
PKA:12.08±0.40(Predicted)
Flash Point:269.7 °C
PSA：45.75000
Density:1.32 g/cm³
LogP:3.16730
Storage Temp.:2-8°C
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:270.0559907
Heavy Atom Count:19
Complexity:374

Purity/Quality:

98% ^*data from raw suppliers

4-[(4-Chlorophenyl)methyl]-1(2H)-phthalazinone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=NNC2=O)CC3=CC=C(C=C3)Cl
Uses Stilbene-related heterocyclic compound with anti-HIV activity. A potent vasorelaxant agent.

Technology Process of 4-(4-chlorobenzyl)phthalazin-1(2H)-one

There total 10 articles about 4-(4-chlorobenzyl)phthalazin-1(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 94801-28-2
(E)-3-(4-chlorobenzylidene)phthalide

: 53242-88-9
4-[(4-chlorophenyl)methyl]-1(2H)-phthalazinone

Guidance literature:: (E)-3-(4-chlorobenzylidene)phthalide; With hydrazine; In ethanol; at 85 ℃; for 15h;

With acetone; In ethanol; at 2 ℃; for 2h;