7-Benzyl-4-oxo-4,7-dihydrothieno[2,3-B]pyridine-5-carboxylic acid

Base Information

Chemical Name:7-Benzyl-4-oxo-4,7-dihydrothieno[2,3-B]pyridine-5-carboxylic acid
CAS No.:67637-79-0
Molecular Formula:C₁₅H₁₁NO₃S
Molecular Weight:285.323
Hs Code.:
DSSTox Substance ID:DTXSID60497851
Wikidata:Q82347623

Synonyms:67637-79-0;7-BENZYL-4-OXO-4,7-DIHYDROTHIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID;DTXSID60497851;AKOS015966461

Suppliers and Price of 7-Benzyl-4-oxo-4,7-dihydrothieno[2,3-B]pyridine-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
7-BENZYL-4-OXO-4,7-DIHYDROTHIENO(2,3-B)PYRIDINE-5-CARBOXYLIC ACID 95.00%
5MG
$ 504.23

Total 1 raw suppliers

Chemical Property of 7-Benzyl-4-oxo-4,7-dihydrothieno[2,3-B]pyridine-5-carboxylic acid

Chemical Property:

Vapor Pressure:1.28E-09mmHg at 25°C
Boiling Point:469.5oC at 760 mmHg
Flash Point:237.8oC
PSA：87.54000
Density:1.462g/cm3
LogP:2.80950
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:285.04596439
Heavy Atom Count:20
Complexity:442

Purity/Quality:: 7-BENZYL-4-OXO-4,7-DIHYDROTHIENO(2,3-B)PYRIDINE-5-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CN2C=C(C(=O)C3=C2SC=C3)C(=O)O

Technology Process of 7-Benzyl-4-oxo-4,7-dihydrothieno[2,3-B]pyridine-5-carboxylic acid

There total 3 articles about 7-Benzyl-4-oxo-4,7-dihydrothieno[2,3-B]pyridine-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 59713-52-9
ethyl α-carboethoxy-β-(N-2-thienylammonium) acrylate

: 67637-79-0
7-benzyl-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: diphenyl ether / 0.5 h / Heating

2: aq. NaOH / 1 h / Heating

3: (i) K₂CO₃, DMF, (ii) /BRN= 385801/

With sodium hydroxide; In diphenylether;

Reference yield:

: 55503-31-6
ethyl 4-hydroxythieno[2,3-b]pyridine-5-carboxylate

: 67637-79-0
7-benzyl-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: aq. NaOH / 1 h / Heating

2: (i) K₂CO₃, DMF, (ii) /BRN= 385801/

With sodium hydroxide;