N-(4-bromophenyl)morpholine-4-carboxamide

Base Information

Chemical Name:N-(4-bromophenyl)morpholine-4-carboxamide
CAS No.:67759-57-3
Molecular Formula:C11H13BrN2O2
Molecular Weight:285.14
Hs Code.:
European Community (EC) Number:667-060-3
ChEMBL ID:CHEMBL1170104

Synonyms:N-(4-bromophenyl)morpholine-4-carboxamide;67759-57-3;F1757-0367;SCHEMBL5219633;CHEMBL1170104;STK260378;AKOS001022030;n-(4-bromophenyl)-4-morpholinecarboxamide;SR-01000025160;SR-01000025160-1;Z56754746

Suppliers and Price of N-(4-bromophenyl)morpholine-4-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(4-bromophenyl)morpholine-4-carboxamide

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:284.01604
Heavy Atom Count:16
Complexity:236

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COCCN1C(=O)NC2=CC=C(C=C2)Br

Technology Process of N-(4-bromophenyl)morpholine-4-carboxamide

There total 5 articles about N-(4-bromophenyl)morpholine-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 15159-40-7
4-morpholinocarbonyl chloride

: 106-40-1
4-bromo-aniline

: 67759-57-3
N-(4-bromophenyl)morpholine-4-carboxamide

Guidance literature:: With triethylamine; In dichloromethane; at 0 ℃; Reflux;
DOI:10.1016/j.ejmech.2010.03.027

Reference yield:

: 103-71-9
phenyl isocyanate

: 67759-57-3
N-(4-bromophenyl)morpholine-4-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: hexane / 25 °C / Cooling with ice

2: 1,3,5-tribromo-1,3,5-triazinane-2,4,6-trione / acetonitrile / 25 °C

With 1,3,5-tribromo-1,3,5-triazinane-2,4,6-trione; In hexane; acetonitrile;
DOI:10.1055/s-0036-1589149

Reference yield:

: 2617-78-9
N-(4-bromophenyl)formamide

: 67759-57-3
N-(4-bromophenyl)morpholine-4-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: bis-[(trifluoroacetoxy)iodo]benzene / 1,2-dichloro-ethane / 0.03 h / 20 °C / Molecular sieve; Inert atmosphere

2: 2 h / 20 °C / Molecular sieve; Inert atmosphere

With bis-[(trifluoroacetoxy)iodo]benzene; In 1,2-dichloro-ethane;
DOI:10.1039/c4nj01668h