N-(4-methoxyphenyl)-4-methylquinolin-2-amine

Base Information

Chemical Name:N-(4-methoxyphenyl)-4-methylquinolin-2-amine
CAS No.:67837-41-6
Molecular Formula:C17H16N2O
Molecular Weight:264.327
Hs Code.:
DSSTox Substance ID:DTXSID90355657
Nikkaji Number:J455.735B
Wikidata:Q82134677
ChEMBL ID:CHEMBL1364400

Synonyms:N-(4-methoxyphenyl)-4-methylquinolin-2-amine;67837-41-6;2-Quinolinamine, N-(4-methoxyphenyl)-4-methyl-;HMS1684G21;Oprea1_638689;Oprea1_787650;MLS000856023;CHEMBL1364400;DTXSID90355657;HMS2686O24;STK838605;AKOS000631230;NCGC00310299-01;SMR000286468;(4-methoxyphenyl)-(4-methylquinolin-2-yl)amine;AB00613278-06;SR-01000400438;SR-01000400438-1

Suppliers and Price of N-(4-methoxyphenyl)-4-methylquinolin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-(4-methoxyphenyl)-4-methylquinolin-2-amine

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:264.126263138
Heavy Atom Count:20
Complexity:301

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NC2=CC=CC=C12)NC3=CC=C(C=C3)OC

Technology Process of N-(4-methoxyphenyl)-4-methylquinolin-2-amine

There total 10 articles about N-(4-methoxyphenyl)-4-methylquinolin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 634-47-9
2-chloro-4-methylquinoline

: 104-94-9
4-methoxy-aniline

: 67837-41-6
(4-methoxyphenyl)(4-methylquinolin-2-yl)amine

Guidance literature:: In butan-1-ol; Heating;

Reference yield: 55.0%

: 4053-40-1
4-methylquinoline 1-oxide

: 459-64-3
4-methoxybenzenediazonium tetrafluoroborate

: 67837-41-6
(4-methoxyphenyl)(4-methylquinolin-2-yl)amine

Guidance literature:: 4-methylquinoline 1-oxide; 4-methoxybenzenediazonium tetrafluoroborate; With acetonitrile; at 120 ℃; for 0.25h; under 6464.52 Torr; Sealed tube; Microwave irradiation;

With hydrogenchloride; In tetrahydrofuran; water; at 50 ℃; for 6h; regioselective reaction;
DOI:10.1021/acs.joc.9b00739