4053-40-1

Basic information

• Product Name: 4-Methylquinoline 1-oxide
• Synonyms: 4-Methylquinoline 1-oxide;Lepidine 1-oxide;Lepidine N-oxide
• CAS NO: 4053-40-1
• Molecular Formula: C₁₀H₉NO
• Molecular Weight: 175.1
• Mol File: 4053-40-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 284.68°C (rough estimate)
• Flash Point: 144.3°C
• Appearance: /
• Density: 1.1202 (rough estimate)
• Vapor Pressure: 0.000831mmHg at 25°C
• Refractive Index: 1.5460 (estimate)
• CAS DataBase Reference: 4-Methylquinoline 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methylquinoline 1-oxide(4053-40-1)
• EPA Substance Registry System: 4-Methylquinoline 1-oxide(4053-40-1)

Safety Data

• Hazardous Substances Data: 4053-40-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H9NO/c1-8-6-7-11(12)10-5-3-2-4-9(8)10/h2-7H,1H3

Upstream product

• 491-35-0 C₆H₄NCH₂CHCCH₂ 
• 281-23-2 adamantane 
• 630-19-3 pivalaldehyde 
• 7732-18-5 water 
• 7722-84-1 dihydrogen peroxide 
• 64-19-7 acetic acid 

Downstream Products

• 6220-93-5 3-hydroxy-4-methylquinoline 
• 6281-32-9 4-quinolylmethanol 
• 607-66-9 4-methylquinolin-2-ol 
• 5632-17-7 4-(chloromethyl)quinoline 
• 10590-69-9 4-methylquinoline-2-carbonitrile 
• 3475-16-9 4-methyl-2-phenylquinoline 1-oxide 
• 4789-76-8 4-methyl-2-phenylquinoline 
• 607-66-9 4-methyl-1,2-dihydroquinolin-2-one 
• 5467-57-2 2-chloroquinoline-4-carboxylic acid 
• 1426249-89-9 4-methyl-2-(4-methoxylbenzenesulfonyl)quinoline-N-oxide 
• 1426249-91-3 4-methyl-2-(4-fluorobenzenesulfonyl)quinoline-N-oxide 
• 1426249-90-2 4-methyl-2-(4-trifluoromethylbenzenesulfonyl)quinoline-N-oxide 
• 92868-77-4 4-methyl-2-((4-nitrophenyl)sulfonyl)quinoline 
• 64789-03-3 4-methyl-2-tosylquinoline 

Relevant articles and documents

Facile, one-step production of niacin (vitamin B3) and other nitrogen-containing pharmaceutical chemicals with a single-site heterogeneous catalyst

Niacin (3-picolinic acid), which is extensively used as vitamin B 3 in foodstuffs and as a cholesterol-lowering agent, along with other oxygenated products of the picolines, 4-methylquinoline, and a variety of pyrimidines and pyridazines, may be produced in a single-step, environmentally benign fashion by combining single-site, open-structure, heterogeneous catalysts witha solid source of active oxygen, namely acetyl peroxyborate (APB), in the absence of an organic solvent. The high activities, selectivities, and the relatively mild conditions employed with this single-site heterogeneous catalyst, coupled with ease of transport, storage, and stability of the solid oxidant, augurs well for the future use of APB in conjunction with other open-structure, single-site catalysts for fine-chemical, pharmaceutical, and agrochemical applications.