4053-40-1

Usage

InChI:InChI=1/C10H9NO/c1-8-6-7-11(12)10-5-3-2-4-9(8)10/h2-7H,1H3

Upstream product

• 491-35-0 C₆H₄NCH₂CHCCH₂ 
• 281-23-2 adamantane 
• 630-19-3 pivalaldehyde 
• 7732-18-5 water 
• 7722-84-1 dihydrogen peroxide 
• 64-19-7 acetic acid 

Downstream Products

• 6220-93-5 3-hydroxy-4-methylquinoline 
• 6281-32-9 4-quinolylmethanol 
• 607-66-9 4-methylquinolin-2-ol 
• 5632-17-7 4-(chloromethyl)quinoline 
• 10590-69-9 4-methylquinoline-2-carbonitrile 
• 491-35-0 C₆H₄NCH₂CHCCH₂ 
• 607-66-9 4-methyl-1,2-dihydroquinolin-2-one 
• 42182-43-4 2-(methylcarbamoyl)-4-methylquinoline 
• 76278-24-5 4-(4-Methyl-quinolin-2-yl)-2-phenyl-4H-oxazol-5-one 
• 83492-20-0 5-(4-Methyl-quinolin-2-yl)-2-phenyl-thiazol-4-one 
• 75003-53-1 5-(4-Methyl-quinolin-2-yl)-3-phenyl-2-thioxo-thiazolidin-4-one 
• 83813-57-4 2-(4-Methyl-1H-quinolin-2-ylidene)-cyclohexane-1,3-dione 
• 83819-53-8 5,5-Dimethyl-2-(4-methyl-1H-quinolin-2-ylidene)-cyclohexane-1,3-dione 
• 5465-88-3 4-methylquinolin-2-yl 4-methylbenzenesulfonate 

Relevant academic research and scientific papers

Facile, one-step production of niacin (vitamin B3) and other nitrogen-containing pharmaceutical chemicals with a single-site heterogeneous catalyst

Niacin (3-picolinic acid), which is extensively used as vitamin B 3 in foodstuffs and as a cholesterol-lowering agent, along with other oxygenated products of the picolines, 4-methylquinoline, and a variety of pyrimidines and pyridazines, may be produced in a single-step, environmentally benign fashion by combining single-site, open-structure, heterogeneous catalysts witha solid source of active oxygen, namely acetyl peroxyborate (APB), in the absence of an organic solvent. The high activities, selectivities, and the relatively mild conditions employed with this single-site heterogeneous catalyst, coupled with ease of transport, storage, and stability of the solid oxidant, augurs well for the future use of APB in conjunction with other open-structure, single-site catalysts for fine-chemical, pharmaceutical, and agrochemical applications.

Trapping of free-radicals in the oxidation of ethers, aldehydes and alkanes by dimethyldioxirane

Alkyl, α-oxyalkyl and acyl radical intermediates in the oxidation of alkanes, ethers and aldehydes by dimethyldioxirane are trapped by protonated quinolines and a free-radical chain is suggested for the α-acetoxylation of ketones.