2-Oxa-6,9,21-triazadocosan-22-oic acid, 1-[2,6-bis(trifluoromethyl)phenyl]-1,4,7,10-tetraoxo-8-(phenylmethyl)-, 1,1-dimethylethyl ester, (8S)-

Base Information

Chemical Name:2-Oxa-6,9,21-triazadocosan-22-oic acid, 1-[2,6-bis(trifluoromethyl)phenyl]-1,4,7,10-tetraoxo-8-(phenylmethyl)-, 1,1-dimethylethyl ester, (8S)-
CAS No.:681447-89-2
Molecular Formula:C37H47F6N3O7
Molecular Weight:759.786
Hs Code.:

2-Oxa-6,9,21-triazadocosan-22-oic acid,
1-[2,6-bis(trifluoromethyl)phenyl]-1,4,7,10-tetraoxo-8-(phenylmethyl)-,
1,1-dimethylethyl ester, (8S)-

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Oxa-6,9,21-triazadocosan-22-oic acid, 1-[2,6-bis(trifluoromethyl)phenyl]-1,4,7,10-tetraoxo-8-(phenylmethyl)-, 1,1-dimethylethyl ester, (8S)-

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MSDS Files:: SDS file from LookChem

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Technology Process of 2-Oxa-6,9,21-triazadocosan-22-oic acid, 1-[2,6-bis(trifluoromethyl)phenyl]-1,4,7,10-tetraoxo-8-(phenylmethyl)-, 1,1-dimethylethyl ester, (8S)-

There total 1 articles about 2-Oxa-6,9,21-triazadocosan-22-oic acid, 1-[2,6-bis(trifluoromethyl)phenyl]-1,4,7,10-tetraoxo-8-(phenylmethyl)-, 1,1-dimethylethyl ester, (8S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.0%

: 681447-88-1
2,6-bis-trifluoromethyl-benzoic acid-3-(2-amino-3-phenyl-propionylamino)-2-oxo-propyl ester p-toluenesulfonic acid salt

: 10436-25-6
11-(tert-butoxycarbonylamino)undecanoic acid

: 681447-89-2
2,6-bis-trifluoromethyl-benzoic acid 3-[2-(11-tert-butoxycarbonylamino-10-methyl-undecanoylamino)-3-phenyl-propionylamino]-2-oxo-propyl ester

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In DMF (N,N-dimethyl-formamide); for 18h;

Reference yield: 31.0%

: 681447-89-2
2,6-bis-trifluoromethyl-benzoic acid 3-[2-(11-tert-butoxycarbonylamino-10-methyl-undecanoylamino)-3-phenyl-propionylamino]-2-oxo-propyl ester

: 5-carboxytetramethylrhodamine succinimidyl ester

: 153088-76-7
(S)-3-benzyloxycarbonylamino-5-bromo-4-oxo-pentanoic acid tert-butyl ester

Guidance literature:: 2,6-bis-trifluoromethyl-benzoic acid 3-[2-(11-tert-butoxycarbonylamino-10-methyl-undecanoylamino)-3-phenyl-propionylamino]-2-oxo-propyl ester; With hydrogenchloride; In 1,4-dioxane; methanol; water; at 20 ℃; for 0.5h;

5-carboxytetramethylrhodamine succinimidyl ester; With N-ethyl-N,N-diisopropylamine; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 2h;