2-(3,4-Dihydroxybenzyl)quinuclidine hydrochloride

Base Information

Chemical Name:2-(3,4-Dihydroxybenzyl)quinuclidine hydrochloride
CAS No.:103660-55-5
Molecular Formula:C14H19 N O2 . Cl H
Molecular Weight:269.771
Hs Code.:
DSSTox Substance ID:DTXSID10908543
ChEMBL ID:CHEMBL1600647
Mol file:103660-55-5.mol

Synonyms:2-(3,4-Dihydroxybenzyl)quinuclidine hydrochloride;103660-55-5;1,2-Benzenediol, 4-(1-azabicyclo(2.2.2)oct-2-ylmethyl)-, hydrochloride;4-(1-Azabicyclo(2.2.2)oct-2-ylmethyl)-1,2-benzenediol hydrochloride;MLS000047817;4-(1-azabicyclo[2.2.2]octan-2-ylmethyl)benzene-1,2-diol;hydrochloride;SMR000033822;CHEMBL1600647;DTXSID10908543;REGID_for_CID_3025501;AKOS024396655;LS-29928;SR-01000496154;SR-01000496154-1;4-[(1-Azabicyclo[2.2.2]octan-2-yl)methyl]benzene-1,2-diol--hydrogen chloride (1/1)

Suppliers and Price of 2-(3,4-Dihydroxybenzyl)quinuclidine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(3,4-Dihydroxybenzyl)quinuclidine hydrochloride

Chemical Property:

Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:269.1182566
Heavy Atom Count:18
Complexity:263

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN2CCC1CC2CC3=CC(=C(C=C3)O)O.Cl

Technology Process of 2-(3,4-Dihydroxybenzyl)quinuclidine hydrochloride

There total 4 articles about 2-(3,4-Dihydroxybenzyl)quinuclidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 21472-89-9
1-azabicyclo[2.2.1]heptan-3-one

: 103660-55-5
2-(3,4-dihydroxybenzyl)quinuclidine

Guidance literature:: Multi-step reaction with 3 steps

1: 79 percent / NaOH / ethanol / 1) 5 h, reflux, 2) 16 h, 20 deg C

2: 90 percent / H₂ / 5percent Pd/C / aq. HCl; methanol / 20 °C

3: 1.32 g / HCl / 1) reflux, 34 h, 2) 4 deg C, 15 h

With sodium hydroxide; hydrogen; palladium on activated charcoal; In hydrogenchloride; methanol; ethanol;
DOI:10.1007/BF00515032

Reference yield:

: 103660-32-8
2-(3,4-dimethoxyphenylmethylene)-3-oxoquinuclidine

: 103660-55-5
2-(3,4-dihydroxybenzyl)quinuclidine

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / H₂ / 5percent Pd/C / aq. HCl; methanol / 20 °C

2: 1.32 g / HCl / 1) reflux, 34 h, 2) 4 deg C, 15 h

With hydrogen; palladium on activated charcoal; In hydrogenchloride; methanol;
DOI:10.1007/BF00515032

Reference yield:

: 120-14-9
3,4-dimethoxy-benzaldehyde

: 103660-55-5
2-(3,4-dihydroxybenzyl)quinuclidine

Guidance literature:: Multi-step reaction with 3 steps

1: 79 percent / NaOH / ethanol / 1) 5 h, reflux, 2) 16 h, 20 deg C

2: 90 percent / H₂ / 5percent Pd/C / aq. HCl; methanol / 20 °C

3: 1.32 g / HCl / 1) reflux, 34 h, 2) 4 deg C, 15 h

With sodium hydroxide; hydrogen; palladium on activated charcoal; In hydrogenchloride; methanol; ethanol;
DOI:10.1007/BF00515032