5-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-1H-indole

Base Information

Chemical Name:5-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-1H-indole
CAS No.:683229-62-1
Molecular Formula:C15H20BNO3
Molecular Weight:273.14
Hs Code.:2934999090
DSSTox Substance ID:DTXSID30681927
Nikkaji Number:J1.979.699J
Wikidata:Q82606107
Mol file:683229-62-1.mol

Synonyms:683229-62-1;5-METHOXY-1H-INDOLE-2-BORONIC ACID PINACOL ESTER;5-METHOXY-2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDOLE;DTXSID30681927;MFCD11858363;MB10199;BS-29364;CS-0175692;FT-0705179;F73890;A867072;5-methoxy-2-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole;2-(5-Methoxy-1H-indole-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Suppliers and Price of 5-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Methoxy-1H-indole-2-boronicacidpinacolester
25mg
$ 45.00

Crysdot
5-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole 95+%
5g
$ 508.00

American Custom Chemicals Corporation
5-METHOXY-1H-INDOLE-2-BORONIC ACID PINACOL ESTER 98.00%
5MG
$ 502.96

Alichem
5-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
5g
$ 548.91

AK Scientific
5-Methoxy-1H-indole-2-boronicacidpinacolester
1g
$ 291.00

Total 12 raw suppliers

Chemical Property of 5-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-1H-indole

Chemical Property:

PSA：43.48000
LogP:2.47570
Storage Temp.:Sealed in dry,Store in freezer, under -20°C
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:273.1536237
Heavy Atom Count:20
Complexity:358

Purity/Quality:

97% ^*data from raw suppliers

5-Methoxy-1H-indole-2-boronicacidpinacolester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=CC3=C(N2)C=CC(=C3)OC

Technology Process of 5-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-1H-indole

There total 3 articles about 5-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 1006-94-6
5-methoxylindole

: 73183-34-3
bis(pinacol)diborane

: 683229-62-1
5-methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

Guidance literature:: bis(pinacol)diborane; With 5-methyl-2-(thiophen-3-yl)pyridine; (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; In tetrahydrofuran; at 20 ℃; for 0.0333333h; Inert atmosphere; Glovebox;

5-methoxylindole; In tetrahydrofuran; at 80 ℃; for 12h; regioselective reaction; Inert atmosphere; Sealed tube;
DOI:10.1021/jacs.0c13415

Reference yield: 53.0%

: 1006-94-6
5-methoxylindole

: 25015-63-8
4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

: 683229-62-1
5-methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

Guidance literature:: With catalyst: [Ir(COD)Cl]2/2bpy; In further solvent(s); under Ar; 5-methoxyindole (60 mmol) added to pinacolborane (2 mmol) + 1.5 mol% (Ir(COD)Cl)2 + 1.5 mol% bpy; stirred (80°C, 6 h); solvent removed (vac., room temp.); residue chromd. (silica gel, CH2Cl2); elem. anal.;
DOI:10.1016/S1381-1169(03)00470-9

Reference yield: 49.0%

: 683229-62-1
5-methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

Guidance literature:: With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine; In 1,4-dioxane; at 20 ℃; Sealed tube;